Molecules that bind to cd94/nkg2a heterodimer polypeptides
US-2024415889-A1 · Dec 19, 2024 · US
US9593164B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9593164-B2 |
| Application number | US-201314086588-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 21, 2013 |
| Priority date | Nov 21, 2012 |
| Publication date | Mar 14, 2017 |
| Grant date | Mar 14, 2017 |
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Bispecific EGFR/c-Met antibodies and methods of making and using the molecules.
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What is claimed: 1. An isolated bispecific epidermal growth factor receptor (EGFR)/hepatocyte growth factor receptor (c-Met) antibody, comprising: a) a first heavy chain (HC1); b) a second heavy chain (HC2); c) a first light chain (LC1); and d) a second light chain (LC2) wherein the HC1, the LC1, the HC2 and the LC2 comprise amino acid sequences of SEQ ID NOs: 199, 200, 201 and 202, respectively. 2. A pharmaceutical composition comprising the bispecific antibody of claim 1 and a pharmaceutically acceptable carrier.
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