Crystalline erlotinib hydrochloride process

US9593083B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9593083-B2
Application numberUS-201314418449-A
CountryUS
Kind codeB2
Filing dateAug 14, 2013
Priority dateSep 4, 2012
Publication dateMar 14, 2017
Grant dateMar 14, 2017

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

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The present invention provides process for preparation of Crystalline Erlotinib HCl (I) Form-SE characterized by X-ray powder diffraction pattern comprising at least 5 characteristic 2θ° peaks selected from the XRPD peak set of 5.60, 10.00, 11.40, 13.00, 13.50, 15.20, 18.40, 20.65, 21.86, 23.5, 31.80, 32.13, 32.80, 34.40±0.20 2θ°, DSC isotherm comprising the endothermic peaks ranging between 213 to 217° C. (Peak −1) and 225 to 235° C. (Peak −2) and IR absorption characteristic peaks at approximately 3278 cm −1 , 1948 cm −1 , 1871 cm −1 , 1632 cm −1 , 1164 cm −1 , 1024 cm −1 , 940 cm −1 and 742 cm −1 useful as active pharmaceutical ingredient in pharmaceutical compositions for the treatment cancer.

First claim

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We claim: 1. Erlotinib hydrochloride (I) crystalline Form-SE characterized by X-ray powder diffraction pattern according to FIG.- 1 .

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What does patent US9593083B2 cover?
The present invention provides process for preparation of Crystalline Erlotinib HCl (I) Form-SE characterized by X-ray powder diffraction pattern comprising at least 5 characteristic 2θ° peaks selected from the XRPD peak set of 5.60, 10.00, 11.40, 13.00, 13.50, 15.20, 18.40, 20.65, 21.86, 23.5, 31.80, 32.13, 32.80, 34.40±0.20 2θ°, DSC isotherm comprising the endotherm…
Who is the assignee on this patent?
Shilpa Medicare Ltd
What technology area does this patent fall under?
Primary CPC classification C07D239/94. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Mar 14 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).