Microbiome identification and bacteriophage formulations
US-2024123002-A1 · Apr 18, 2024 · US
Porphyrin—modified antimicrobial peptides for application as indicators of microbial targets
US9581594B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9581594-B2 |
| Application number | US-201414208189-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 13, 2014 |
| Priority date | Mar 14, 2013 |
| Publication date | Feb 28, 2017 |
| Grant date | Feb 28, 2017 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Porphyrin-modified antimicrobial peptides as described here may be used as indicators of the presence of microbial targets. Their application may be as (for example) (1) fluorescent indicators in a microarray format, (2) fluorescence or absorbance based indicators in traditional solution based applications, or (3) reflectance based indicators for use in reagent-less detection platforms.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of detecting bacterial cells, comprising: providing a porphyrin-modified antimicrobial peptide comprising a porphyrin covalently attached to an antimicrobial peptide; contacting the porphyrin-modified antimicrobial peptide in a microtiter plate with the bacterial cells, thereby causing a conformational change in the porphyrin-modified antimicrobial peptide; and detecting with a microtiter plate reader a change in fluorescence and/or absorbance of the porphyrin-modified antimicrobial peptide caused by the conformational change, corresponding to a presence or absence of the bacterial cells, wherein the method is operable to detect the bacterial cells without use of an additional optically-active reagent, wherein the porphyrin is 5-mono(4-carboxyphenyl)-10,15,20-triphenyl porphine and the antimicrobial peptide is covalently attached to the porphyrin via carbodiimide-mediated coupling, and wherein said antimicrobial peptide is Indolicidin or Cecropin A-melittin hybrid peptide CeMe(L).
Assignees
Inventors
Classifications
- G01N33/56911Primary
Bacteria · CPC title
with at least one carbon-silicon bond · CPC title
Organic compounds · CPC title
Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic · CPC title
Aromatic hydrocarbons · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9581594B2 cover?
- Porphyrin-modified antimicrobial peptides as described here may be used as indicators of the presence of microbial targets. Their application may be as (for example) (1) fluorescent indicators in a microarray format, (2) fluorescence or absorbance based indicators in traditional solution based applications, or (3) reflectance based indicators for use in reagent-less detection platforms.
- Who is the assignee on this patent?
- Taitt Chris Rowe, White Brandy J, Us Navy
- What technology area does this patent fall under?
- Primary CPC classification G01N33/56911. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Feb 28 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).