Novel melanoma antigen peptide and uses thereof
US-2015132329-A1 · May 14, 2015 · US
US9573975B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9573975-B2 |
| Application number | US-201214402803-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 22, 2012 |
| Priority date | May 22, 2012 |
| Publication date | Feb 21, 2017 |
| Grant date | Feb 21, 2017 |
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The present invention relates to a melanoma antigen peptide comprising the amino acids sequence selected in the group consisting of SEQ ID NO: 1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4 or SEQ ID NO:5 or a function-conservative variant thereof. Moreover the invention also relates to a melanoma antigen peptide according to the invention for use in the prevention or the treatment of melanoma in patient.
Opening claim text (preview).
The invention claimed is: 1. A melanoma antigen peptide having less than 40 amino acids comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4 and SEQ ID NO:5; or a fusion peptide comprising said amino acid sequence and a melanoma antigen peptide comprising the amino acids motif: TX2NDECWPX9(SEQ ID NO: 23), wherein X2 is leucine, methionine, valine, isoleucine or glutamine and X9 is alanine, valine or leucine; or a composition comprising said melanoma antigen peptide or said fusion peptide. 2. A method of treating melanoma in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of an agent selected from the group consisting of: i) a melanoma antigen peptide according to claim 1 , ii) a fusion protein according to claim 1 , or iii) a composition according to claim 1 . 3. The method according to claim 2 wherein the patient is genotyped with HLA-DQβ1*0201 or HLA-DQβ1*0202 alleles.
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having 12 to 20 amino acids (gastrins C07K14/595; somatostatins C07K14/655; melanotropins C07K14/68) · CPC title
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