Methods for detecting Ehrlichia infection

US9568473B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9568473-B2
Application numberUS-201514851747-A
CountryUS
Kind codeB2
Filing dateSep 11, 2015
Priority dateNov 13, 2009
Publication dateFeb 14, 2017
Grant dateFeb 14, 2017

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention provides an isolated and purified heat shock protein 60 (Hsp60) peptide having the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a vaccine against Ehrlichia comprising a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to an antibody directed against a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a method of determining whether a subject is infected with Ehrlichia , comprising the steps of: contacting a sample from a subject with the antibody described herein; and detecting a resulting antibody reaction, wherein a positive reaction indicates the subject is infected with Ehrlichia.

First claim

Opening claim text (preview).

What is claimed is: 1. A method for detecting Ehrlichia in a sample comprising the steps of: ( a ) contacting the sample with an antibody that binds a 21 amino acid peptide having the sequence of SEQ ID NO:2 to form an antibody/peptide complex; and ( b ) detecting the complex. 2. The method of claim 1 , wherein the sample is from a dog. 3. The method of claim 1 , wherein the sample is serum. 4. The method of claim 1 , wherein said Ehrlichia is Ehrlichia chaffeensis, Ehrlichia muris, Ehrlichia ewingii, Ehrlichia ruminantium or Ehrlichia canis.

Assignees

Inventors

Classifications

  • Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues · CPC title

  • from Richettsiales (O) · CPC title

  • Rickettsiales (O) · CPC title

  • Rickettsiales, e.g. Anaplasma · CPC title

  • Antibacterial agents · CPC title

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What does patent US9568473B2 cover?
The present invention provides an isolated and purified heat shock protein 60 (Hsp60) peptide having the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a vaccine against Ehrlichia comprising a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to an antibody directed against a peptide homologous to the amino acid…
Who is the assignee on this patent?
Walker David H, Thomas Sunil, Univ Texas
What technology area does this patent fall under?
Primary CPC classification G01N33/56911. Mapped technology areas include Physics.
When was this patent published?
Publication date Tue Feb 14 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).