Microbiome identification and bacteriophage formulations
US-2024123002-A1 · Apr 18, 2024 · US
US9568473B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9568473-B2 |
| Application number | US-201514851747-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 11, 2015 |
| Priority date | Nov 13, 2009 |
| Publication date | Feb 14, 2017 |
| Grant date | Feb 14, 2017 |
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The present invention provides an isolated and purified heat shock protein 60 (Hsp60) peptide having the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a vaccine against Ehrlichia comprising a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to an antibody directed against a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a method of determining whether a subject is infected with Ehrlichia , comprising the steps of: contacting a sample from a subject with the antibody described herein; and detecting a resulting antibody reaction, wherein a positive reaction indicates the subject is infected with Ehrlichia.
Opening claim text (preview).
What is claimed is: 1. A method for detecting Ehrlichia in a sample comprising the steps of: ( a ) contacting the sample with an antibody that binds a 21 amino acid peptide having the sequence of SEQ ID NO:2 to form an antibody/peptide complex; and ( b ) detecting the complex. 2. The method of claim 1 , wherein the sample is from a dog. 3. The method of claim 1 , wherein the sample is serum. 4. The method of claim 1 , wherein said Ehrlichia is Ehrlichia chaffeensis, Ehrlichia muris, Ehrlichia ewingii, Ehrlichia ruminantium or Ehrlichia canis.
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