Chromatography column frame and method of conducting maintenance on and packing of a chromatography column

Patent metadata

Field	Value
Publication number	US-9566538-B2
Application number	US-201314409446-A
Country	US
Kind code	B2
Filing date	Jun 21, 2013
Priority date	Jun 21, 2012
Publication date	Feb 14, 2017
Grant date	Feb 14, 2017

Abstract

A chromatography column frame comprising at least two legs, a support arrangement connected to said at least two legs, and a holder connected to said support arrangement. Said holder is arranged to releasably hold an adaptor rod of a chromatography column, so that the adaptor rod is prevented to move in a horizontal direction and so the adaptor rod is allowed to move in a vertical direction.

First claim

The invention claimed is:

1. A frame for supporting a chromatography column, comprising:
at least two legs;
a support arrangement connected to said at least two legs; and
a holder connected to said support arrangement,
wherein the chromatography column comprises a tubular housing; a first end unit removably connected to a first end of the tubular housing; a second end unit removably connected to a second end of the tubular housing; an adaptor assembly moveable within said tubular housing;
and an adaptor rod connected to said adaptor assembly, which adaptor rod is arranged to extend through an opening in the first end unit; and
a stopper arranged on the support arrangement adapted to interact with an axial groove in the adaptor rod, so that the adaptor rod is prevented from pivoting in the holder,
wherein said holder is arranged to releasably hold the adaptor rod of the chromatography column, so that the adaptor rod is prevented to move in a horizontal direction and so the adaptor rod is allowed to move in a vertical direction.

2. The frame according to claim 1 , wherein the holder comprises at least one support plate provided with a recess for the adaptor rod.

3. The frame according to claim 2 , the at least one support plate is provided with a bearing surface for a driver arranged on the adaptor rod.

4. The frame according to claim 3 , wherein the driver is a threaded sleeve arranged to interact with threads on the adaptor rod, so that the adaptor rod moves in the vertical direction when pivoting the sleeve.

5. The frame according to claim 2 , wherein two support plates are arranged on the support arrangement, each plate is provided with a recess, which recesses together define an opening for the adaptor rod.

6. The frame according to claim 5 , wherein at least one of the support plates are removably connected to the support arrangement.

7. The frame according to claim 1 , wherein the support arrangement is adjustable along said legs, so that the frame may be adapted for chromatography columns of different sizes.

8. The frame according to claim 1 , further comprising wheels arranged on the frame, so that the frame may be moved to and from the position of the chromatography column.

Assignees

• Ge Healthcare Bio Sciences Ab

Inventors

• Haglund Bjorn
• Jiang Cheng
• Kling Martin

Classifications

• G01N2030/562

  packing · CPC title

• G01N30/6047 Primary

  with supporting means; Holders · CPC title

• G01N30/6017

  Fluid distributors · CPC title

• B01D15/22 Primary

  relating to the construction of the column · CPC title

• G01N30/56

  Packing methods or coating methods · CPC title