Triple combination therapies for anti-aging
US-2024316086-A1 · Sep 26, 2024 · US
US9566225B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9566225-B2 |
| Application number | US-51461307-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 12, 2007 |
| Priority date | Nov 13, 2006 |
| Publication date | Feb 14, 2017 |
| Grant date | Feb 14, 2017 |
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An oral composition capable of identifying a condition within the oral cavity by causing a visual contrast between the condition and the hard and soft tissues of the oral cavity has at least one disclosing agent. The disclosing agent can fluoresce in order to highlight conditions within the oral cavity.
Opening claim text (preview).
What is claimed is: 1. A dentifrice composition comprising: a disclosing agent capable of fluorescing, thereby highlighting plaque within an oral cavity, wherein the disclosing agent is dibromofluorescein, and wherein the dentifrice composition comprises from about 0.05% to 0.1% dibromofluorescein; and wherein the dibromofluorescein does not cause staining; from about 0.0025% to about 5.0% of a fluoride source; and from about 10% to about 50% of an abrasive; wherein the dibromofluorescein is not readily visually perceptible under ambient light after rinsing and/or expectorating; wherein the dibromofluorescein fluoresces in response to electromagnetic energy having wavelengths that are within the visible spectrum; wherein the dibromofluorescein emits electromagnetic energy greater than 530 nm; wherein the dibromofluorescein is capable of fluorescing after a user rinses and/or expectorates the dentifrice composition from the oral cavity; wherein the dentifrice composition is suitable for home use. 2. An oral hygiene kit comprising: a dentifrice composition comprising: from about 0.05% to 0.1% of a disclosing agent capable of fluorescing, thereby highlighting plaque within an oral cavity, wherein the disclosing agent is dibromofluorescein; wherein the dibromofluorescein emits electromagnetic energy greater than 530 nm; wherein the dibromofluorescein does not cause staining; wherein the dentifrice composition is suitable for home use; wherein the dibromofluorescein fluoresces in response to electromagnetic energy having wavelengths that are within the visible spectrum; and wherein the dibromofluorescein is not readily visually perceptible under ambient light after rinsing and/or expectorating; from about 0.0025% to about 5.0% of a fluoride source; and from about 10% to about 50% of an abrasive; wherein the disclosing agent is capable of fluorescing after a user rinses or expectorates the dentifrice composition from the oral cavity; an oral hygiene device comprising a body having a handle region and a head region, wherein an energy source is disposed in the head region, wherein the energy source is capable of providing visible light and wherein the energy applied to the disclosing agent causes the disclosing agent to fluoresce and wherein the energy source includes an LED wherein the LED has a Flux Density at a Representative Tooth Surface of from about 0.1 mW/cm 2 to about 20 mW/cm 2 . 3. A method of identifying plaque within the oral cavity at home, the method comprising: applying a dentifrice composition to the oral cavity for a period of time from about 5 seconds to about 120 seconds, wherein the dentifrice composition comprises: from about 0.05% to 0.1% of a disclosing agent which is dibromofluorescein wherein the dibromofluorescein does not cause staining; and from about 0.0025% to about 5.0% of a fluoride source; and from about 10% to about 50% of an abrasive; rinsing and/or expectorating the dentifrice composition from the oral cavity wherein the dibromofluorescein is not readily visually perceptible under ambient light after rinsing and/or expectorating; wherein the dibromofluorescein fluoresces in response to electromagnetic energy having wavelengths that are within the visible spectrum; and wherein the dibromofluorescein emits electromagnetic energy greater than 530 nm; applying energy from an energy source to the oral cavity wherein the energy source is capable of providing visible light and wherein the energy source includes an LED wherein the LED has a Flux Density at a Representative Tooth Surface of from about 0.1 mW/cm 2 to about 20 mW/cm 2 ; viewing the plaque within the oral cavity; and performing a cleaning operation to reduce the presence of the plaque. 4. The method of claim 3 wherein the dentifrice composition is applied to the oral cavity by an oral hygiene device comprising: a body having a handle region and a head region; and a plurality of bristles disposed in the head region, at least a portion of the plurality of bristles defining a substantially orange color. 5. The method of claim 4 wherein the head region comprises the energy source. 6. The method of claim 3 further comprising the step of applying a mouthrinse comprising the disclosing agent. 7. The dentifrice composition of claim 1 wherein the composition comprises greater than about 0.07% and less than about 0.08% dibromofluorescein. 8. The dentifrice composition of claim 1 further comprising an opacifying agent selected from the group consisting of titanium dioxide, mica, mica coated titanium dioxide, polypropylene, polyester particulates, and combinations thereof. 9. The dentifrice composition of claim 8 wherein the opacifying agent comprises titanium dioxide. 10. The dentifrice composition of claim 1 wherein at least a portion of the dentifrice composition is opaque. 11. The oral hygiene kit of claim 2 wherein the dentifrice composition comprises greater than about 0.07% and less than about 0.08% dibromofluorescein. 12. The oral hygiene kit of claim 2 wherein the dentifrice composition further comprises an opacifying agent selected from the group consisting of titanium dioxide, mica, mica coated titanium dioxide, polypropylene, polyester particulates, and combinations thereof. 13. The oral hygiene kit of claim 12 wherein the opacifying agent comprises titanium dioxide. 14. The method of claim 3 wherein the dentifrice composition comprises greater than about 0.07% and less than about 0.08% dibromofluorescein. 15. The method of claim 3 wherein the dentifrice composition further comprises an opacifying agent selected from the group consisting of titanium dioxide, mica, mica coated titanium dioxide, polypropylene, polyester particulates, and combinations thereof. 16. The method of claim 15 wherein the opacifying agent comprises titanium dioxide. 17. The method of claim 3 wherein at least a portion of the dentifrice composition is opaque.
Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis · CPC title
having 6-membered rings or their condensed derivatives, e.g. coumarin · CPC title
Luminescent, Fluorescent; Optical brighteners; Photosensitizers · CPC title
interchangeably {removable bristle carriers} · CPC title
Toothbrush for cleaning the teeth or dentures (A61C17/16 takes precedence; bristles arrangements for toothbrushes A46B9/04) · CPC title
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