Point-and-click programming for deep brain stimulation using real-time monopolar review trendlines

Patent metadata

Field	Value
Publication number	US-9561380-B2
Application number	US-201615012698-A
Country	US
Kind code	B2
Filing date	Feb 1, 2016
Priority date	Aug 28, 2012
Publication date	Feb 7, 2017
Grant date	Feb 7, 2017

Abstract

A system and method for selecting leadwire stimulation parameters includes a processor iteratively performing, for each of a plurality of values for a particular stimulation parameter, each value corresponding to a respective current field: (a) shifting the current field longitudinally and/or rotationally to a respective plurality of locations about the leadwire; and (b) for each of the respective plurality of locations, obtaining clinical effect information regarding a respective stimulation of the patient tissue produced by the respective current field at the respective location; and displaying a graph plotting the clinical effect information against values for the particular stimulation parameter and locations about the leadwire, and/or based on the obtained clinical effect information, identifying an optimal combination of a selected value for the particular stimulation parameter and selected location about the leadwire at which to perform a stimulation using the selected value.

First claim

What is claimed is:

1. A computer-implemented method for selecting electrical stimulation parameters for a leadwire implanted in patient tissue, the method comprising:
receiving, by a computer processor, user input of a point within a graph, the user input provided by point and click within the graph, the graph plotting obtained therapeutic effect and adverse side effect values for a plurality of values of a particular stimulation parameter against locations about the leadwire, the user-input point corresponding to a single value for the particular stimulation parameter and a single location about the leadwire;
determining, by the processor, a combination of values for the particular stimulation parameter for each of a plurality of electrodes of the leadwire; and
at least one of (a) displaying on a monitor, by the processor, the determined values of the particular stimulation parameter or (b) initiating, a signal, by the processor, to apply the determined values of the particular stimulation parameter to an implanted pulse generator that causes the leadwire to produce a stimulation.

2. The method of claim 1 , wherein the locations correspond to actual locations of electrodes of the leadwire and virtual locations of electrodes of the leadwire corresponding to a current field producible by a combination of a respective subset of the electrodes of the leadwire.

3. The method of claim 1 , wherein the graph is three dimensional, and further plots the obtained therapeutic effect and adverse side effect values against values for a second stimulation parameter.

4. The method of claim 1 , wherein the locations differ longitudinally and rotationally about the leadwire.

5. The method of claim 4 , wherein the graph is three has three dimensions, variations in longitudinal location about the leadwire being plotted along a first one of the dimensions of the graph and variations in rotational location about the leadwire being plotted along a second one of the dimensions of the graph.

6. The method of claim 1 , wherein the stimulation parameter is one of i) amplitude of a current, ii) pulse width of a current, and iii) frequency of a current.

7. The method of claim 1 , wherein the combination of values are applied in the step initiating a signal to apply the determined values of the particular stimulation parameter to an implanted pulse generator that causes the leadwire to produce a stimulation by interleaving current supply to different ones of a plurality of electrodes.

8. The method of claim 1 , wherein the locations correspond to actual locations of electrodes of the leadwire and virtual locations of electrodes of the leadwire corresponding to a current field producible by a combination of a respective subset of the electrodes of the leadwire.

9. The method of claim 8 , further comprising identifying within the graph, a region whose plotted therapeutic effect values are lower than its adverse side effect values, with a greatest distance between plotted values of the therapeutic effect and adverse side effect.

10. The method of claim 1 , wherein the user-input point is shifted in response to user input of a shill instruction by selection of a control, each selection of Which is interpreted by the processor as an instruction to shift in a respective direction by a predetermined amount.

11. The method of claim 1 , further comprising:
iteratively performing the following for each of the plurality of values for the particular stimulation parameter, each value corresponding to a respective current field:
positioning, by a computer processor, the current field at each of a respective plurality of locations about the leadwire; and
for each of the respective plurality of locations, obtaining, by the processor, one or more therapeutic effect or adverse side effect values regarding a respective stimulation of the patient tissue produced by the respective current field at the respective location.

12. The method of claim 11 , wherein the locations differ longitudinally and rotationally about the leadwire.

13. The method of claim 11 , wherein the positioning is performed by shifting the current field at least one of longitudinally and rotationally.

14. The method of claim 13 , wherein the shifting is performed in response to user input of a shift instruction by selection of a control, each selection of which is interpreted by the processor as an instruction to shift in a respective direction by a predetermined amount.

15. The method of claim 14 , wherein the combination of values is applied by interleaving current supply to different ones of the electrodes.

16. The method of claim 12 , wherein the stimulation parameter is one of i) amplitude, ii) pulse width, and iii) frequency.

17. The method of claim 11 , wherein the locations correspond to actual locations of electrodes of the leadwire and virtual locations of electrodes of the leadwire corresponding to a current field producible by a combination of a respective subset of the electrodes of the leadwire.

Assignees

• Boston Scient Neuromodulation Corp

Inventors

• Carcieri Stephen
• Chen Dean
• Moffitt Micahel A

Classifications

• A61N1/372

  Arrangements in connection with the implantation of stimulators · CPC title

• A61N1/3605

  Implantable neurostimulators for stimulating central or peripheral nerve system · CPC title

• G06F19/3406

  Physics · mapped topic

• A61N1/36185

  Selection of the electrode configuration · CPC title

• A61N1/0534

  Electrodes for deep brain stimulation · CPC title