Multiple dosage injector

Patent metadata

Field	Value
Publication number	US-9561333-B2
Application number	US-201414568857-A
Country	US
Kind code	B2
Filing date	Dec 12, 2014
Priority date	Aug 5, 2008
Publication date	Feb 7, 2017
Grant date	Feb 7, 2017

Abstract

A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.

First claim

What is claimed is:

1. A medicament dispensing mechanism, comprising:
a housing having a longitudinal axis;
a plunger rod configured for ejecting the doses of medicament from a chamber;
an actuation mechanism that comprises a driver and a trigger, the trigger having a ready position and a fired position with respect to the housing,
wherein:
the trigger is configured for manipulation by a user for successive movement in a dosing motion along the longitudinal axis from the ready position to the fired position to cause the plunger rod to eject one of the doses of a predetermined volume, and in a resetting motion from the fired position to the ready position;
in the dosing motion, the trigger causes the driver and the plunger rod to rotate about the longitudinal axis;
the housing defines a first track and the trigger defines a first projection, the first track being configured for receiving the first projection and defines the dosing motion and the resetting motion with respect to the housing;
the trigger defines a second track and the driver defines a second projection, the second track being configured for receiving the second projection and applying a force to the second projection during the dosing motion to rotate the driver, and to allow the resetting motion without rotating the driver;
the first track defines a succession of a plurality of the ready positions interposed in continuous series by a plurality of the fired positions and paths for the corresponding dosing motions and resetting motions therebetween,
the second track comprises a plurality of driving portions for causing the trigger to rotate the driver in each of the dosing motions connected in continuous series by alternately applying a force to the second projection during successive dosing motions of the trigger to rotate the driver in a driving direction;
the first track has a first tab disposed therein with a free end configured for engaging the first projection and preventing rearward movement of the trigger from the fired position against the direction of the dosing motion; and
the first track has a second tab disposed therein with a free end configured for engaging the first projection and for preventing rearward movement of the trigger from the ready position against the direction of the resetting motion.

2. The dispensing mechanism of claim 1 , wherein each of the plurality of ready positions and each of the plurality of fired positions are disposed in sequence with each other, and wherein the plurality of ready positions are circumferentially spaced about the housing.

3. The dispensing mechanism of claim 1 , wherein the first tab and the second tab comprise an anti-retrograde mechanism, wherein the anti-retrograde mechanism is associated with the trigger for preventing rearward movement thereof from the ready position against the direction of the resetting motion, and wherein the anti-retrograde mechanism is associated with the trigger for preventing rearward movement thereof from the fired position against the direction of the dosing motion.

4. The dispensing mechanism of claim 3 , wherein:
the driver is associated with the plunger rod for causing the plunger rod to eject said one of the doses;
the anti-retrograde mechanism is configured for preventing rearward movement of the driver with respect to the trigger against the dosing motion; and
the trigger includes stepped surfaces facing a relative path of the second projection during the dosing motion, the stepped surfaces configured for engaging the second projection during rearward movement therebetween for preventing rearward movement of the trigger.

5. The dispensing mechanism of claim 4 , wherein:
the stepped surfaces are substantially flat and face axially;
the second projection defines a notch to receive an edge of the stepped surfaces; and
the trigger comprising a sloped surface opposite the stepped surfaces and engaged with the second projection during the dosing motion to cause the trigger to cam the driver for rotating and driving the plunger rod.

6. The dispensing mechanism of claim 5 , wherein the anti-retrograde mechanism is configured for preventing rearward movement of the driver with respect to the housing, and the predetermined volume is fixed.

7. The dispensing mechanism of claim 5 , wherein the anti-retrograde mechanism is configured for preventing the rearward movement of the plunger rod only after a predetermined number of doses have been ejected from the chamber and disabling the actuation mechanism by including a flexible arm disposed within the housing, the plunger rod being configured to force a portion of the flexible arm axially outwardly after the predetermined number of doses have been ejected from the chamber, and the flexible arm being configured to engage a portion of the trigger to prevent further motion of the trigger in the resetting motion to disable the actuation mechanism.

8. The dispensing mechanism of claim 1 , wherein the second track has a resetting portion aligned substantially axially to allow the resetting motion of the trigger without rotating the driver.

9. The dispensing mechanism of claim 1 , wherein the driving direction is opposite from the direction of rotation of the trigger in the resetting motion.

10. A medicament dispensing mechanism, comprising:
a housing having a longitudinal axis;
a plunger rod configured for ejecting doses of medicament from a chamber, each of the doses having a predetermined volume;
an actuation mechanism that comprises a driver and a trigger, the trigger having a ready position and a fired position with respect to the housing,
wherein:
the trigger is configured to be manipulated by a user for successive movement in a dosing motion along the longitudinal axis from the ready position to the fired position to cause the plunger rod to eject one of the doses, and movement in a resetting motion from the fired position to the ready position;
in the dosing motion, the trigger causes the driver and the plunger rod to rotate about the longitudinal axis;
the housing defines a first track and the trigger defines a first projection, the first track configured to receive the first projection and defines the dosing motion and the resetting motion with respect to the housing;
the first track includes a first horizontal portion, a second horizontal portion axially spaced from the first horizontal portion, and a vertical portion connecting the first horizontal portion and the second horizontal portion such that the resetting motion includes a first rotation of the trigger about the longitudinal axis, axial translation of the trigger, and a second rotation of the trigger about the longitudinal axis, the first horizontal portion including an upper boundary and a lower boundary, each of the upper boundary and the lower boundary extending horizontally beyond the vertical portion;
the trigger defines a second track and the driver defines a second projection, the second track being configured to receive the second projection and applying a force to the second projection during the dosing motion to rotate the driver, and to allow the resetting motion without rotating the driver;
the first track defines a succession of a plurality of the ready positions interposed in continuous series by a plurality of the fired positions and paths for the corresponding dosing motions and resetting motions therebetween;
the second track comprises a plurality of driving portions for causing the trigger to rotate the driver in each of the dosing motions connected in continuous series by alternately applying a force to the second projection during successive dosing motions of the trigger to rotate the driver in a driving direction.

Assignees

• Antares Pharma Inc

Inventors

• Cox Janice L
• Rust Matthew H
• Kramer Thomas E
• Hoeft Peter A

Classifications

• A61M5/31566

  Means improving security or handling thereof · CPC title

• A61M2005/2403

  Ampoule inserted into the ampoule holder · CPC title

• A61M5/31593 Primary

  Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir · CPC title

• A61M2005/2407

  from the rear · CPC title

• A61M5/31545

  Setting modes for dosing · CPC title