Intersession monitoring for blood fluid removal therapy

Patent metadata

Field	Value
Publication number	US-9561316-B2
Application number	US-201213424429-A
Country	US
Kind code	B2
Filing date	Mar 20, 2012
Priority date	Apr 29, 2011
Publication date	Feb 7, 2017
Grant date	Feb 7, 2017

Abstract

Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patent parameters. By comparing the patient's current parameters to past parameters in response to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.

First claim

What is claimed is:

1. A method of using a blood fluid removal system for tracking one or more physiological parameters of a patient, wherein the blood fluid removal system comprises:
(a) a blood fluid removal medium configured to remove blood from the patient, wherein the blood enters the medium, a fluid contained in the blood is removed from the blood, and the blood exits the medium;
(b) one or more control elements configured to control (i) a rate at which the medium removes fluid from the blood or (ii) concentration of electrolytes or pH in the blood that exits the medium;
(c) one or more sensors configured to monitor the one or more physiological parameters of the patient wherein the physiological parameters are one or more selected from the group consisting of blood pressure, heart rate, pH and electrolyte concentration, the one or more sensors sensing signals from one or more of the blood and a tissue of the patient; and
(d) control electronics comprising memory and a processor, wherein the control electronics are in operable communication with the one or more sensors and are operably coupled to the one or more control elements, wherein the control electronics are programmed to carry out the method of or for tracking the one or more physiological parameters of the patient, comprising:
storing system parameters from a first blood fluid removal session in memory;
acquiring a first set of data regarding the one or more physiological parameters of the patient following the first session but before a second blood fluid removal session;
storing the first data set in a most effective to date data set in memory;
associating the first system parameters in an increased effectiveness lookup table with the first data set;
storing system parameters from the second blood fluid removal session in memory;
acquiring a second set of data regarding the one or more physiological parameters of the patient following the second blood fluid removal session; and
if at least one value of the second data set from the second blood fluid removal session is closer to a target value than a corresponding at least one value of the first data set from the first blood fluid removal session: replacing the first data set in the most effective to date data set in memory with the second data set; storing in the increased effectiveness lookup table data regarding the second data set; and
associating data regarding the second system parameters with the second data set.

2. The method of claim 1 , further comprising:
storing the first data set in a least effective to date data set in memory;
associating the first system parameters in a decreased effectiveness lookup table with the first data set;
if the at least one value of the second data set from the second blood fluid removal session is not closer to the target value than the corresponding at least one value of the first data set from the first blood fluid removal session: replacing the first data set in the least effective to date data set memory with the second data set; storing in the decreased effectiveness lookup table data regarding the second data set; and associating data regarding the second system parameters with the second data set.

3. The method of claim 1 , further comprising:
storing system parameters for a third blood fluid removal session in memory; acquiring a third set of data regarding the one or more physiological parameters of the patient following the third session; and
if at least one value of the third data set from the third blood fluid removal session is closer to the target value than a corresponding at least one value stored in the most effective to date data set memory: replacing the data set in the most effective to date data set memory with the third data set; and storing in the increased effectiveness lookup table data regarding the third data set, and associating data regarding the third system parameters with the third data set.

4. The method of claim 1 , further comprising:
storing system parameters from a fourth blood fluid removal session in memory; acquiring a fourth set of data regarding the one or more physiological parameters of the patient following the fourth session; and
if at least one value of the fourth data set from the fourth blood fluid removal session is not closer to the target value than a corresponding at least one value stored in the least effective to date data set memory: replacing the data set in the least effective to date data set memory with the fourth data set; and storing in the decreased effectiveness lookup table data regarding the fourth data set, and associating data regarding the fourth system parameters with the fourth data set.

5. The method of claim 1 , further comprising:
acquiring a fifth set of data regarding one or more physiological parameters of the patient; comparing the fifth data set to the increased effectiveness lookup table; and
setting system parameters for a next blood fluid removal session to system parameters associated with the data set stored in the increased effectiveness lookup table if at least one parameter of a data set stored in the increased effectiveness lookup table is within a predetermined range of the fifth data set.

6. The method of claim 1 , wherein the at least one of the one or more physiological parameters of the patient are selected from the group consisting of blood pressure, heart rate, pH and concentration of an electrolyte.

7. The method of claim 6 , wherein the electrolyte is potassium.

8. The method of claim 1 , wherein the system parameters comprise one or more of fluid removal rate and concentration of one or more electrolyte.

9. A blood fluid removal system, comprising:
a blood fluid removal medium configured to remove blood from a patient, wherein the blood enters the medium,
a fluid contained in the blood is removed from the blood, and the blood exits the medium;
one or more control elements configured to control (i) a rate at which the medium removes fluid from the blood or (ii) concentration of electrolytes or pH in the blood that exits the medium;
one or more sensors configured to monitor one or more physiological parameters of the patient wherein the physiological parameters are one or more selected from the group consisting of blood pressure, heart rate, pH and electrolyte concentration, the one or more sensors sensing signals from one or more of the blood and a tissue of the patient; and
control electronics comprising memory and a processor, wherein the control electronics are in operable communication with the one or more sensors and are operably coupled to the one or more control elements,
wherein the control electronics are programmed to carry out a first method of tracking the one or more physiological parameters of the patient comprising steps of:
storing system parameters from a first blood fluid removal session in memory;
acquiring a first set of data regarding the one or more physiological parameters of the patient following the first session but before a second blood fluid removal session; storing the first data set in a most effective to date data set in memory;
associating the first system parameters in an increased effectiveness lookup table with the first data set; storing system parameters from the second blood fluid removal session in memory; acquiring a second set of data regarding the one or more physiological parameters of the patient following the second blood fluid removal session; and
if at least one value of the second data set from the second blood fluid removal session is closer to a target value than a corresponding at least one value of the first data set from the first blood fluid removal session, replacing the first data set in the most e

Assignees

• Gerber Martin
• Lyu Suping
• Pudil Bryant
• Medtronic Inc

Inventors

• Gerber Martin
• Lyu Suping
• Pudil Bryant

Classifications

• A61M2205/50

  with microprocessors or computers · CPC title

• A61M2205/3375

  Acoustical, e.g. ultrasonic, measuring means · CPC title

• A61M2205/3306

  Optical measuring means · CPC title

• B01D2321/12

  Use of permeate · CPC title

• A61M2205/3334

  Measuring or controlling the flow rate · CPC title