Doxycycline composition

US9561242B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9561242-B2
Application numberUS-201615013122-A
CountryUS
Kind codeB2
Filing dateFeb 2, 2016
Priority dateJul 9, 2014
Publication dateFeb 7, 2017
Grant dateFeb 7, 2017

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to a once daily pharmaceutical composition comprising doxycycline, a controlled-release polymer, and one or more pharmaceutically acceptable excipients. The invention further provides a method of treatment of rosacea by administering such pharmaceutical composition. A process of preparing such pharmaceutical composition is also provided.

First claim

Opening claim text (preview).

We claim: 1. A once daily pharmaceutical composition comprising doxycycline, a controlled-release polymer, and one or more pharmaceutically acceptable excipients, wherein the pharmaceutical composition contains up to 40 mg of doxycycline. 2. The once daily pharmaceutical composition according to claim 1 , wherein the pharmaceutical composition contains from 24 mg to 40 mg of doxycycline. 3. The once daily pharmaceutical composition according to claim 1 , wherein the pharmaceutical composition contains 40 mg of doxycycline. 4. The once daily pharmaceutical composition according to claim 1 , wherein the pharmaceutical composition contains 36 mg of doxycycline. 5. The once daily pharmaceutical composition according to claim 1 , wherein the pharmaceutical composition contains 32 mg of doxycycline. 6. The once daily pharmaceutical composition according to claim 1 , wherein the pharmaceutical composition contains 30 mg of doxycycline. 7. The once daily pharmaceutical composition according to claim 1 , wherein the doxycycline is present as a salt, hydrate, or a solvate. 8. The once daily pharmaceutical composition according to claim 7 , wherein the doxycycline is present as doxycycline hyclate. 9. The once daily pharmaceutical composition according to claim 7 , wherein the doxycycline is present as doxycycline monohydrate. 10. The once daily pharmaceutical composition according to claim 1 , wherein the pharmaceutical composition is a capsule or a tablet. 11. The once daily pharmaceutical composition according to claim 1 , wherein the pharmaceutical composition is in the form of pellets, beads, beadlets, granules, spheres or spheroids, minitablets, particles, or powders. 12. The once daily pharmaceutical composition according to claim 10 , wherein the pharmaceutical composition is a capsule filled with one or more of pellets, beads, beadlets, granules, spheres or spheroids, minitablets, particles, or powders. 13. The once daily pharmaceutical composition according to claim 1 , wherein the pharmaceutical composition exhibits a reduced food effect such that the food effect on C max is less than 40% and/or AUC 0-t is less than 20% as compared to when the pharmaceutical composition is administered in a fasted state. 14. A method of treating rosacea by administering to a person in need thereof a once daily pharmaceutical composition comprising doxycycline, a controlled-release polymer, and one or more pharmaceutically acceptable excipients, wherein the pharmaceutical composition contains up to 40 mg of doxycycline.

Assignees

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Classifications

  • obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates · CPC title

  • containing drug in at least two layers or in the core and in at least one outer layer · CPC title

  • Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose · CPC title

  • A61K31/65Primary

    Tetracyclines · CPC title

  • with microcapsules or coated microparticles according to A61K9/50 · CPC title

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Frequently asked questions

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What does patent US9561242B2 cover?
The present invention relates to a once daily pharmaceutical composition comprising doxycycline, a controlled-release polymer, and one or more pharmaceutically acceptable excipients. The invention further provides a method of treatment of rosacea by administering such pharmaceutical composition. A process of preparing such pharmaceutical composition is also provided.
Who is the assignee on this patent?
Sun Pharmaceutical Ind Ltd
What technology area does this patent fall under?
Primary CPC classification A61K31/65. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Feb 07 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).