Devices and methods for percutaneous access, hemostasis, and closure

Patent metadata

Field	Value
Publication number	US-9554787-B2
Application number	US-201414499822-A
Country	US
Kind code	B2
Filing date	Sep 29, 2014
Priority date	Mar 17, 2008
Publication date	Jan 31, 2017
Grant date	Jan 31, 2017

Abstract

The present invention provides methods and devices for obtaining percutaneous access, maintaining hemostasis, and providing closure of openings in tissues of the body. In particular, the present invention provides methods and devices for maintaining hemostasis and providing closure surgical incisions of the left ventricular apex of the heart.

First claim

We claim:

1. A method for occluding blood flow through an incision in a coronary wall of a human heart comprising inserting into said incision a medical closure device comprising:
a cylinder element;
a proximal expanded element that extends circumferentially around the entire circumference of said cylinder element, wherein said proximal expanded element is configured to adopt a reduced profile configuration upon inserting said proximal expanded element into a confined space and to resiliently readopt a high profile configuration upon exit from said confined space; and
a distal expanded element that extends circumferentially around the entire circumference of said cylinder element, wherein said distal expanded element is configured to adopt a reduced profile configuration upon inserting said distal expanded element into a confined space and to resiliently readopt a high profile configuration upon exit from said confined space;
wherein when deployed through the incision in the coronary wall of a human heart said distal expanded element forms a seal against the inner surface of the coronary wall, said proximal expanded element forms a seal against the outer surface of the coronary wall, and said medical closure device occludes blood flow through the incision without the need for thrombus formation; and
wherein said medical closure device comprises one or more lumens through said cylinder element that allow access through the incision from the exterior of the heart to the interior of the heart.

2. The method of claim 1 , wherein the incision is within the coronary wall of the left ventricle.

3. The method of claim 2 , wherein the incision is within the left ventricular apex.

4. The method of claim 3 , wherein, when said medical closure device is deployed through the incision in the coronary wall of a human heart said distal expanded element forms a seal against the inner surface of the coronary wall that approximates an inner surface of the left ventricular apex and said proximal expanded element forms a seal against the outer surface of the coronary wall that approximates an outer surface of the left ventricular apex.

5. The method of claim 1 , wherein at least one of said one or more lumens comprise a one-way valve.

6. The method of claim 1 , wherein said medical closure device comprises a metal fabric skeleton.

7. The method of claim 6 , wherein said metal fabric skeleton comprises one or more shape memory materials.

8. The method of claim 1 , wherein said medical closure device comprises a blood-impermeable skin.

9. The method of claim 8 , wherein said blood-impermeable skin comprises a polymer coating.

Assignees

• Univ Northwestern

Inventors

• Mccarthy Patrick M
• Gnanashanmugam Swaminadhan
• Periyanayagam Usha
• Lin Ingrid
• Ralph Leah
• Lubeck Christopher

Classifications

• A61B2017/00867

  shape memory effect · CPC title

• A61B2017/3425

  for internal organs, e.g. heart ports · CPC title

• A61B17/0057 Primary

  Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009) · CPC title

• A61B2017/00575

  for closure at remote site, e.g. closing atrial septum defects · CPC title

• A61B2017/00243

  cardiac · CPC title