Medical device and methods of monitoring a patient with renal dysfunction

Patent metadata

Field	Value
Publication number	US-9554725-B2
Application number	US-87887310-A
Country	US
Kind code	B2
Filing date	Sep 9, 2010
Priority date	Aug 3, 2010
Publication date	Jan 31, 2017
Grant date	Jan 31, 2017

Abstract

Embodiments relate to a method of monitoring physiological parameters of a patient with renal dysfunction. The method includes electrically connecting one or more medical device electrodes with a measurement site of a patient, generating one or more first stimulation signals sufficient to provide input physiological parameters specific to the patient, measuring one or more first bioimpedance values from the generated signals, analyzing at least one of the input physiological parameters within the one or more first bioimpedance values and generating a personalized dialysis program. The systems and methods can further provide essentially real-time data of patient undergoing treatment and control of treatment to a patient.

First claim

The invention claimed is:

1. A medical treatment system, comprising:
a sensor device connected to a patient undergoing treatment relating to hydration, wherein the sensor device is an adherent device removably attached to the patient, the sensing device including:
a measuring interface at a measurement site of a patient;
one or more electrodes to generate one or more stimulation signals, positioned at the measuring interface and in electrical contact with the measurement site;
circuitry to measure one or more bioimpedance values, as a result of the generated stimulation signals from the one or more electrodes;

a processor to identify one or more physiological parameters, including renal parameters, from the one or more bioimpedance values; and
a treatment device to apply hydration therapy to the patient based at least in part on the physiological parameters, wherein based on the identified physiological parameters and a delay parameter the processor communicates treatment instructions to the treatment device to control fluid removed from the patient, wherein the delay parameter represents a time lag between a fluid removed from the patient and interstitial fluid level represented by the measured bioimpedance values.

2. The medical treatment system of claim 1 , wherein the processor determines a rate of fluid removal from the patient.

3. The medical treatment system of claim 2 , wherein the treatment device is a dialysis treatment device that removes fluid from the patient at the determined fluid removal rate.

4. The medical treatment system of claim 1 , wherein the processor determines a quantity of fluid to be removed from the patient.

5. The medical treatment system of claim 4 , wherein the treatment device is a dialysis treatment device that removes the quantity of fluid determined by the processor.

6. The medical treatment system of claim 3 , wherein the processor is remote from the sensing device.

7. The medical treatment system of claim 1 , wherein the one or more physiological parameters comprise one or more of a fluid retention value, a electrolyte quantity value, or a hydration level value.

8. The medical treatment device of claim 1 , wherein the processor is further configured to determine a baseline of the patient for one or more of a fluid retention value, electrolyte quantity value or hydration level value from the bioimpedance values.

9. The medical treatment device of claim 1 , wherein the one or more stimulation signals include a first signal for establishing baseline physiological data and a subsequent signal for determining a spot check of the patient's status.

10. The medical treatment device of claim 9 , wherein one of the first signal and the subsequent signal include a frequency where electrolytes are known to resist an electrical current.

11. The medical treatment device of claim 1 , wherein the one or more stimulation signals include a frequency sweep.

12. The medical treatment system of claim 1 , wherein the processor system is further adapted to analyze the one of more physiological parameters and generate a personalized dialysis program.

13. The medical treatment system of claim 2 , wherein determining a rate at which fluid is removed from the patient includes determining the rate at the start of the therapy and decreasing the rate when a threshold is met.

14. The medical treatment system of claim 1 , wherein the delay parameter is determined from a study of a population of patients.

15. The medical treatment system of claim 2 , wherein the processor determines a rate at which diuretics are administered to the patient.

16. The medical treatment system of claim 1 , wherein the sensor device communicates bioimpedance values wirelessly to the processor.

17. The medical treatment system of claim 1 , wherein the processor communicates treatment instructions wirelessly to the treatment device.

18. The medical treatment system of claim 1 , wherein the treatment device is a dialysis machine that removes fluid directly from the patient based on treatment instructions received from the processor.

Assignees

• Katra Rodolphe
• Chakravarthy Niranjan
• Libbus Imad
• Medtronic Monitoring Inc

Inventors

• Katra Rodolphe
• Chakravarthy Niranjan
• Libbus Imad

Classifications

• A61B5/0537 Primary

  Measuring body composition by impedance, e.g. tissue hydration or fat content · CPC title

• A61B5/0295

  using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography · CPC title

• A61B5/0538 Primary

  invasively, e.g. using a catheter · CPC title

• A61B5/021

  Measuring pressure in heart or blood vessels · CPC title

• A61B5/4836

  Diagnosis combined with treatment in closed-loop systems or methods (A61B5/0036 takes precedence) · CPC title