Capillary dialyzers

Patent metadata

Field	Value
Publication number	US-9550019-B2
Application number	US-201314409201-A
Country	US
Kind code	B2
Filing date	Jun 20, 2013
Priority date	Jun 21, 2012
Publication date	Jan 24, 2017
Grant date	Jan 24, 2017

Abstract

A capillary dialyzer comprises: a) a housing; a bundle of semi-permeable hollow fiber membranes; c) end walls supporting the first and second ends of the hollow fiber membranes; d) a first end cap covering a first end of the housing and a second end cap covering a second end of the housing; e) an inlet and an outlet; f) support rings; and g) sealing rings interposed between the end wall and the first end cap and between the end wall and the second end cap, respectively. A circular groove of the end cap which receives the wall of the housing comprises indentations for creating a fluid connection between the inside of the capillary dialyzer and its exterior when the end caps are mounted on the housing but have not yet been welded to the housing.

First claim

The invention claimed is:

1. A capillary dialyzer comprising:
a) a housing defining a longitudinally extending internal chamber including a first end and a second end;
b) a bundle of semi-permeable hollow fiber membranes disposed within the internal chamber and extending longitudinally from the first end of the housing to the second end of the housing, the hollow fiber membranes having an outer surface, and a first end and a second end corresponding to the first end and the second end of the internal chamber;
c) end wall supports for supporting the first and second ends of the hollow fiber membranes within the internal chamber so as to sealingly separate the first and second ends of the hollow fiber membranes from the outer surface of the hollow fiber membranes between the first and second ends thereof;
d) a first end cap covering the first end of the housing and a second end cap covering the second end of the housing, the first and second end caps being applied to the first and second ends of the housing in a fluid-tight manner;
e) an inlet for the introduction of a fluid into the internal chamber and an outlet for the evacuation of a fluid from the internal chamber at a location between the first and second ends of the housing;
f) support rings disposed between the end wall supports and the housing at the first and second ends of the internal chamber, each support ring includes a number of ridges distributed circumferentially and defining gaps therebetween; and
g) sealing rings interposed between one of the end wall supports and the first end cap and between another of the end wall supports and the second end cap, respectively;
wherein a circular groove of the end cap which receives the wall of the housing comprises indentations, which create a fluid conduit between the inside of the capillary dialyzer and its exterior when the end caps are mounted on the housing, and the end caps are fixed to the housing by a weld disposed to close the fluid conduit;
wherein header sections of the housing comprise notches on the inside surface which extend from the mouth of the housing to the end of a ledge inside the housing on which the support ring is positioned.

2. The capillary dialyzer of claim 1 wherein the end caps have an inner surface which is axially symmetrical with regard to a longitudinal axis of the end cap and an inner surface having the form of a funnel and comprising, in the direction of increasing diameter, a first section taking the form of at least one of a cylinder and a truncated cone, a middle section taking the form of a torus segment and having a radius of 7.0±0.1 mm, and a third section taking the form of a truncated cone, wherein the diameter of the base of the third section is 39.8±0.1 mm and the angle between the base of the third section and the lateral surface of the third section is 9.53±0.05°, and the outer diameter of the end cap is 55.8±0.1 mm.

3. The capillary dialyzer of claim 2 , wherein the inner diameter of the middle section of the housing is 38.0±0.1 mm and the inner diameter of the mouth of the housing is 49.6±0.1 mm.

4. The capillary dialyzer of claim 1 wherein the end caps have an inner surface which is axially symmetrical with regard to a longitudinal axis of the end cap and an inner surface having the form of a funnel and comprising, in the direction of increasing diameter, a first section taking the form of at least one of a cylinder and a truncated cone, a middle section taking the form of a torus segment and having a radius of 7.0±0.1 mm, and a third section taking the form of a truncated cone, wherein the diameter of the base of the third section is 36.1±0.1 mm and the angle between the base of the third section and the lateral surface of the third section is 8.85±0.05°, and the outer diameter of the end cap is 52.1±0.1 mm.

5. The capillary dialyzer of claim 4 , wherein the inner diameter of the middle section of the housing is 31.5±0.1 mm and the inner diameter of the mouth of the housing is 45.9±0.1 mm.

6. The capillary dialyzer of claim 4 , wherein the inner diameter of the middle section of the housing is 34.0±0.1 mm and the inner diameter of the mouth of the housing is 45.9±0.1 mm.

7. The capillary dialyzer of claim 1 wherein each support ring includes a level section defined between adjacent ones of the number of ridges, wherein the level section includes a bore extending therethrough.

8. A capillary dialyzer comprising:
a) a housing defining a longitudinally extending internal chamber including a first end and a second end;
b) a bundle of semi-permeable hollow fiber membranes disposed within the internal chamber and extending longitudinally from the first end of the housing to the second end of the housing, the hollow fiber membranes having an outer surface, and a first end and a second end corresponding to the first end and the second end of the internal chamber;
c) end wall supports for supporting the first and second ends of the hollow fiber membranes within the internal chamber so as to sealingly separate the first and second ends of the hollow fiber membranes from the outer surface of the hollow fiber membranes between the first and second ends thereof;
d) a first end cap covering the first end of the housing and a second end cap covering the second end of the housing, the first and second end caps being applied to the first and second ends of the housing in a fluid-tight manner;
e) an inlet for the introduction of a fluid into the internal chamber and an outlet for the evacuation of a fluid from the internal chamber at a location between the first and second ends of the housing;
f) support rings disposed between the end wall supports and the housing at the first and second ends of the internal chamber, each support ring includes a number of ridges distributed circumferentially and defining gaps therebetween; and
g) sealing rings interposed between one of the end wall supports and the first end cap and between another of the end wall supports and the second end cap, respectively.

9. The capillary dialyzer of claim 8 wherein each support ring includes a level section defined between adjacent ones of the number of ridges, wherein the level section includes a bore extending therethrough.

10. The capillary dialyzer of claim 8 wherein a circular groove of the end cap which receives a wall of the housing comprises indentations, which create a fluid conduit between the inside of the capillary dialyzer and its exterior when the end caps are mounted on the housing, and the end caps are fixed to the housing by a weld disposed to close the fluid conduit.

11. The capillary dialyzer of claim 10 wherein the end caps have an inner surface which is axially symmetrical with regard to a longitudinal axis of the end cap and an inner surface having the form of a funnel and comprising, in the direction of increasing diameter, a first section taking the form of at least one of a cylinder and a truncated cone, a middle section taking the form of a torus segment and having a radius of 7.0±0.1 mm, and a third section taking the form of a truncated cone, wherein the diameter of the base of the third section is 39.8±0.1 mm and the angle between the base of the third section and the lateral surface of the third section is 9.53±0.05°, and the outer diameter of the end cap is 55.8±0.1 mm.

12. The capillary dialyzer of claim 11 wherein the inner diameter of the middle section of the housing is 38.0±0.1 mm and the inner diameter of the mouth of the housing is 49.6±0.1 mm.

13. The capillary dialyzer of claim 10 wherein the end caps have an inner surface which is axially symmetrical with regard to a longitudinal axis of the end cap

Assignees

• Gambro Lundia Ab

Inventors

• Buck Reinhold
• Henle Roland
• Eichinger Juergen

Classifications

• A61M2205/75

  with filters · CPC title

• B01D65/003

  Membrane bonding or sealing · CPC title

• A61M2207/00

  Methods of manufacture, assembly or production · CPC title

• B01D2313/21

  Specific headers, end caps · CPC title

• A61M2202/0413

  Blood · CPC title