Breast prostheses, methods of manufacturing breast prostheses, and methods of treatment using breast prostheses

Patent metadata

Field	Value
Publication number	US-9549812-B2
Application number	US-201314371291-A
Country	US
Kind code	B2
Filing date	Jan 10, 2013
Priority date	Jan 13, 2012
Publication date	Jan 24, 2017
Grant date	Jan 24, 2017

Abstract

Improved breast prostheses, methods of making breast prostheses, and methods of treatment using such breast prostheses are described.

First claim

What is claimed is:

1. A prosthesis comprising a tissue expander and one or more samples of graft material, wherein the tissue expander comprises resorbable tabs and the one or more samples of graft material comprise apertures, and wherein the one or more samples of graft material are attached to the tissue expander by engaging the resorbable tabs on the tissue expander to the apertures on the one or more samples of graft material.

2. A method of making an implantable prosthesis comprising providing a tissue expander and one or more samples of graft material, wherein the tissue expander comprises resorbable tabs and the one or more samples of graft material comprise apertures; and
attaching the one or more samples of graft material to the tissue expander by causing the resorbable tabs on the tissue expander to engage the apertures on the one or more samples of graft material.

3. A method of making an implantable prosthesis comprising preparing a shell of a silicone breast implant or tissue expander;
providing one or more samples of graft material sized and shaped to conform to a portion of a surface of the breast implant or tissue expander, wherein the graft material is an adipose extracellular tissue matrix that has been treated to produce a three-dimensional porous, or sponge-like material;
attaching the graft material to the shell of the breast implant or tissue expander prior to curing the shell of the silicone breast implant or tissue expander; and
curing the shell of the breast implant or tissue expander and the graft material.

4. The method of claim 3 , wherein the graft material is an acellular tissue matrix.

5. The method of claim 4 , wherein the shell of the breast implant or tissue expander and the adipose acellular tissue matrix are cured such that the curing temperature does not reach a temperature greater than 30° C.

6. The method of claim 4 , wherein the shell of the breast implant or tissue expander and the adipose acellular tissue matrix are cured such that the curing temperature does not exceed 25° C.

7. The method of claim 3 , wherein the shell of the breast implant or tissue expander and the adipose extracellular tissue matrix are cured at a temperature between 80° C. to 110° C.

8. The method of claim 3 , wherein the graft material is removed from the breast implant or the tissue expander after the curing step.

9. A prosthesis comprising a tissue expander and one or more samples of graft material, wherein the tissue expander comprises resorbable barbs and the one or more samples of graft material comprise slits, and wherein the one or more samples of graft material are attached to the tissue expander by engaging the resorbable barbs on the tissue expander to the slits on the one or more samples of graft material.

10. A prosthesis comprising a tissue expander and one or more samples of graft material, wherein the tissue expander comprises resorbable barbs and the one or more samples of graft material comprise mesh, and wherein the one or more samples of graft material are attached to the tissue expander by engaging the resorbable barbs on the tissue expander to the mesh on the one or more samples of graft material.

11. A method of making an implantable prosthesis comprising providing a tissue expander and one or more samples of graft material, wherein the tissue expander comprises resorbable barbs and the one or more samples of graft material comprise slits; and
attaching the one or more samples of graft material to the tissue expander by engaging the resorbable barbs on the tissue expander to the slits on the one or more samples of graft material.

12. A method of making an implantable prosthesis comprising providing a tissue expander and one or more samples of graft material, wherein the tissue expander comprises resorbable barbs and the one or more samples of graft material comprise mesh; and
attaching the one or more samples of graft material to the tissue expander by engaging the resorbable barbs on the tissue expander to the mesh on the one or more samples of graft material.

13. A method of making an implantable prosthesis comprising preparing a shell of a silicone breast implant or tissue expander;
providing one or more samples of graft material sized and shaped to conform to a portion of a surface of the breast implant or tissue expander;
attaching the graft material to the shell of the breast implant or tissue expander prior to curing the shell of the silicone breast implant or tissue expander;
curing the shell of the breast implant or tissue expander and the graft material; and
removing the graft material from the breast implant or tissue expander after the curing step.

14. The method of claim 13 , wherein the graft material is an acellular tissue matrix.

15. The method of claim 14 , wherein the shell of the breast implant or tissue expander and the acellular tissue matrix are cured such that the curing temperature does not reach a temperature greater than 30° C.

16. The method of claim 14 , wherein the shell of the breast implant or tissue expander and the acellular tissue matrix are cured such that the curing temperature does not exceed 25° C.

17. The method of claim 13 , wherein the graft material is an adipose extracellular tissue matrix that has been treated to produce a three-dimensional porous, or sponge-like material.

18. The method of claim 17 , wherein the shell of the breast material or tissue expander and the adipose extracellular tissue matrix are cured at a temperature between 80° C. to 110° C.

19. The method of claim 13 , wherein the graft material is removed from the breast implant or tissue expander after the curing step.

Assignees

• Lifecell Corp

Inventors

• Shetty Dhanuraj
• Barere Aaron
• Friedman Evan
• Bowley Melissa Richter
• Roock Timothy

Classifications

• A61F2210/0076

  multilayered, e.g. laminated structures · CPC title

• A61F2240/001

  Designing or manufacturing processes · CPC title

• A61F2220/005

  using adhesives · CPC title

• B29K2083/00

  Use of polymers having silicon, with or without sulfur, nitrogen, oxygen, or carbon only, in the main chain, as moulding material · CPC title

• A61F2/0059

  Cosmetic or alloplastic implants (A61F2/10 - A61F2/16, A61F2/28 take precedence) · CPC title