Biological fluid sampling transfer device and biological fluid separation and testing system

Patent metadata

Field	Value
Publication number	US-9549700-B2
Application number	US-201414251693-A
Country	US
Kind code	B2
Filing date	Apr 14, 2014
Priority date	Apr 15, 2013
Publication date	Jan 24, 2017
Grant date	Jan 24, 2017

Abstract

A blood separation and testing system for a blood sample is disclosed. The blood separation and testing system includes a blood sampling transfer device adapted to receive a blood sample, a blood separation device, and a blood testing device. The blood separation device is adapted to receive a portion of the blood sampling transfer device such that with the blood sampling transfer device received within the blood separation device and a rotational force applied to the blood sampling transfer device, a plasma portion of the blood sample is separated from a cellular portion of the blood sample. The blood testing device is adapted to receive a portion of the blood sampling transfer device to analyze the plasma portion of the blood sample and obtain test results.

First claim

What is claimed is:

1. A biological fluid sampling transfer device, comprising:
a housing having a resiliently deformable upper portion, a lower portion removably connectable to the upper portion, the lower portion having an inlet port, an outlet port, and a flow channel, the inlet port and the outlet port in fluid communication via the flow channel, the upper portion transitionable between an undeformed position and a deformed position; and
a puncturing element, a portion of which is disposed within the housing and adapted for movement between a pre-actuated position wherein the puncturing element is retained within the housing and a puncturing position wherein the puncturing element extends through the inlet port of the lower portion of the housing,
wherein, when the lower portion of the housing is removed from the upper portion of the housing, the inlet port and the flow channel in the lower portion are sealed and the puncturing element is contained within the upper portion of the housing.

2. The biological fluid sampling transfer device of claim 1 , wherein the biological fluid sampling transfer device is adapted to receive a multi-component blood sample.

3. The biological fluid sampling transfer device of claim 2 , wherein the multi-component blood sample comprises a first cellular component and a second plasma component.

4. The biological fluid sampling transfer device of claim 2 , wherein the flow channel is adapted to receive the blood sample via the inlet port.

5. The biological fluid sampling transfer device of claim 1 , wherein actuation of the upper portion from the undeformed position to the deformed position moves the puncturing element from a pre-actuated position to a puncturing position.

6. The biological fluid sampling transfer device of claim 5 , wherein after the puncturing element moves to the puncturing position, the upper portion returns to its undeformed position and returns the puncturing element to the pre-actuated position.

7. The biological fluid sampling transfer device of claim 6 , wherein with the blood sample received within the flow channel, the lower portion is removable from the upper portion.

8. The biological fluid sampling transfer device of claim 1 , further comprising an adhesive disposed on an outside surface of the lower portion.

9. The biological fluid sampling transfer device of claim 1 , further comprising a check valve in the upper portion.

10. A biological fluid sampling transfer device adapted to receive a multi-component blood sample, the biological fluid sampling transfer device comprising:
a housing having a resiliently deformable upper portion, a lower portion removably connectable to the upper portion, the lower portion having an inlet port, an outlet port, and a flow channel, the inlet port and the outlet port in fluid communication via the flow channel, the flow channel adapted to receive the blood sample via the inlet port, the upper portion transitionable between an undeformed position and a deformed position; and
a puncturing element, a portion of which is disposed within the housing and adapted for movement between a pre-actuated position wherein the puncturing element is retained within the housing and a puncturing position wherein the puncturing element extends through the inlet port of the lower portion of the housing,
wherein actuation of the upper portion from the undeformed position to the deformed position moves the puncturing element from the pre-actuated position to the puncturing position,
wherein after the puncturing element moves to the puncturing position, the upper portion returns to the undeformed position and the puncturing element returns to the pre-actuated position, and
wherein, when the lower portion of the housing is removed from the upper portion of the housing, the inlet port and the flow channel in the lower portion are sealed and the puncturing element is contained within the upper portion of the housing.

11. The biological fluid sampling transfer device of claim 10 , wherein with the blood sample received within the flow channel, the lower portion is removable from the upper portion.

12. The biological fluid sampling transfer device of claim 10 , further comprising an adhesive disposed on an outside surface of the lower portion.

13. The biological fluid sampling transfer device of claim 10 , further comprising a check valve in the upper portion.

Assignees

• Becton Dickinson Co

Inventors

• Fletcher Gary D
• Gelfand Craig A
• Marchiarullo Daniel J
• Newby C Mark
• Rothenberg Ashley Rachel

Classifications

• A61B5/150778

  having complementary physical shapes for indexing or registration purposes · CPC title

• A61B5/150221

  Valves · CPC title

• A61B5/15105

  Purely manual piercing, i.e. the user pierces the skin without the assistance of any driving means or driving devices · CPC title

• A61B5/150748

  Having means for aiding positioning of the piercing device at a location where the body is to be pierced (means for aiding positioning of devices for bringing media into the body A61M5/427, locating blood vessels A61B5/489) · CPC title

• B01L2200/10

  Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept · CPC title