Method for a rapid determination of spatially resolved magnetic resonance relaxation parameters in an area of examination

Patent metadata

Field	Value
Publication number	US-9547059-B2
Application number	US-201313866328-A
Country	US
Kind code	B2
Filing date	Apr 19, 2013
Priority date	Apr 20, 2012
Publication date	Jan 17, 2017
Grant date	Jan 17, 2017

Abstract

In a method for a rapid determination of spatially resolved magnetic resonance relaxation parameters in an area of examination, a preparation pulse is radiated into the area of examination. During the relaxation of the longitudinal magnetization, spatially encoded magnetic resonance signals are acquired at a minimum of two different points in time using a fast magnetic resonance sequence. At each inversion time, an image data record is reconstructed from the magnetic resonance signals, which are elastically registered to each other. From the recorded image data records, values of magnetic resonance relaxation parameters are spatially accurately determined.

First claim

We claim as our invention:

1. A method for rapid determination of spatially resolved magnetic resonance (MR) relaxation parameters in an examination region, comprising:
operating a magnetic resonance data acquisition unit to radiate a radio-frequency preparation pulse into an examination area of a subject in the data acquisition unit, thereby producing relaxation of longitude in all magnetization of nuclear spins in the examination area;
during the relaxation of the longitudinal magnetization, operating said MR data acquisition unit to acquire spatially encoded MR signals originating from said nuclear spins at a minimum of two different inversion times, according to a fast magnetic resonance data acquisition sequence;
at any of said inversion times, reconstructing an image data record from the MR signals;
in a processor, elastically bringing at least two of said image data records into registration with each other, thereby producing registered image data records; and
in said processor, identifying, from the registered image data records, MR relaxation parameters in a spatially correct relationship, and making said MR relaxation parameters available in electronic form at an output of said processor.

2. A method as claimed in claim 1 comprising radiating said preparation pulse as an inversion pulse.

3. A method as claimed in claim 1 comprising radiating said preparation pulse as a saturation pulse.

4. A method as claimed in claim 1 comprising using the longitudinal relaxation constant T 1 as said magnetic resonance relaxation parameter.

5. A method as claimed in claim 1 comprising using the transverse relaxation constant T 2 as said magnetic resonance relaxation parameter.

6. A method as claimed in claim 1 comprising employing a gradient echo sequence as said fast magnetic resonance sequence.

7. A method as claimed in claim 6 comprising employing a TrueFISP sequence as said gradient echo sequence.

8. A method as claimed in claim 1 comprising acquiring said MR signals during one cardiac cycle of the examination subject.

9. A method as claimed in claim 1 comprising bringing said at least two image data sets into registration elastically by implementing a synthetic estimation of each of said image data records, with each synthetic estimation of an image data record being determined in an iterative process from the respective image data record.

10. A method as claimed in claim 1 comprising successively, at each cardiac cycle of the examination subject, generating magnetic resonance relaxation parameter maps, and displaying said maps in real time.

11. A method as claimed in claim 10 comprising bringing said image data records into registration elastically for each inversion time, and generating said MR relaxation parameters for each inversion time.

12. A method as claimed in claim 11 comprising generating a synthetic image data record for each cardiac phase in each cardiac cycle that exhibit a predetermined target contrast.

13. A method as claimed in claim 12 comprising, for each inversion time, displaying the MR parameters together with the respective image data records.

14. A method as claimed in claim 13 comprising displaying the MR parameters superimposed with said image data records.

15. A method as claimed in claim 1 comprising, in said processor, from said values of said MR relaxation parameters, generating an MR relaxation parameter map.

Assignees

• Greiser Andreas
• Schmitt Peter
• Xue Hui
• Siemens Ag

Inventors

• Greiser Andreas
• Schmitt Peter
• Xue Hui

Classifications

• G01R33/50 Primary

  based on the determination of relaxation times {, e.g. T1 measurement by IR sequences; T2 measurement by multiple-echo sequences} · CPC title

• G01R33/56509

  due to motion, displacement or flow, e.g. gradient moment nulling (G01R33/567 takes precedence) · CPC title

• G01R33/56

  Image enhancement or correction, e.g. subtraction or averaging techniques {, e.g. improvement of signal-to-noise ratio and resolution} · CPC title