Heterocyclic modulators of lipid synthesis
US-2024400552-A1 · Dec 5, 2024 · US
Radiosynthesis of tau radiopharmaceuticals
US9546167B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9546167-B2 |
| Application number | US-201615087681-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 31, 2016 |
| Priority date | May 31, 2013 |
| Publication date | Jan 17, 2017 |
| Grant date | Jan 17, 2017 |
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- Title
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Abstract
Official abstract text for this publication.
This disclosure relates to a one-step method for preparing the tau radiopharmaceutical, [18F]T807, using an unprotected or protected precursor (e.g., tert-butyl 7-(6-nitropyridin-3-yl)-5H-pyrido[4,3-b]indole-5-carboxylate).
First claim
Opening claim text (preview).
What is claimed is: 1. A compound of formula (I): wherein Z is a leaving group. 2. The compound of claim 1 , wherein the leaving group comprises: triflate, mesylate, nonaflate, hexaflate, tosylate, nosylate, brosylate, perfluoroalkyl sulfonate, tetraphenylborate, hexafluorophosphate, trifluoroacetate, tetrafluoroborate, perchlorate, perfluoroalkylcarboxylate, nitro, azide, chloride, bromide, or iodide. 3. The compound of claim 1 , wherein the leaving group is tetramethylammonium triflate. 4. The compound of claim 1 , wherein the compound of formula (I) is: 5. A compound of formula (I): wherein Z is a leaving group comprising tetramethylammonium. 6. The compound of claim 5 , wherein the leaving group further comprises: triflate, mesylate, nonaflate, hexaflate, tosylate, nosylate, brosylate, and perfluoroalkyl sulfonate. 7. The compound of claim 5 , wherein the leaving group further comprises triflate.
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Heterocyclic compounds · CPC title
- C07D471/04Primary
Ortho-condensed systems · CPC title
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Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9546167B2 cover?
- This disclosure relates to a one-step method for preparing the tau radiopharmaceutical, [18F]T807, using an unprotected or protected precursor (e.g., tert-butyl 7-(6-nitropyridin-3-yl)-5H-pyrido[4,3-b]indole-5-carboxylate).
- Who is the assignee on this patent?
- Massachusetts Gen Hospital
- What technology area does this patent fall under?
- Primary CPC classification C07D471/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jan 17 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).