Compounds and compositions for intracellular delivery of therapeutic agents
US-2018273467-A1 · Sep 27, 2018 · US
US9540330B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9540330-B2 |
| Application number | US-201113994606-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 15, 2011 |
| Priority date | Dec 15, 2010 |
| Publication date | Jan 10, 2017 |
| Grant date | Jan 10, 2017 |
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The invention relates to (among other things) oligomer-containing hydantoin compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits one or more advantages over corresponding compounds lacking the oligomer.
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What is claimed is: 1. A pharmaceutical composition comprising a compound of formula: and pharmaceutically acceptable salts thereof, wherein: n is 1 to 12; and the compound is present in a dosage form. 2. The pharmaceutical composition of claim 1 , further comprising a pharmaceutically acceptable excipient. 3. The pharmaceutical composition of claim 1 , wherein n is 1 or 3-9.
with hetero atoms or acyl radicals directly attached to ring nitrogen atoms · CPC title
Two oxygen atoms, e.g. hydantoin · CPC title
the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol · CPC title
Antiepileptics; Anticonvulsants · CPC title
Human Necessities · mapped topic
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