Method of making oil-in-water emulsified composition using corona-core microgel emulsifying agent

Patent metadata

Field	Value
Publication number	US-9539554-B2
Application number	US-201514851195-A
Country	US
Kind code	B2
Filing date	Sep 11, 2015
Priority date	Dec 22, 2011
Publication date	Jan 10, 2017
Grant date	Jan 10, 2017

Abstract

The present invention provides a corona-core microgel emulsifying agent composed of a copolymer obtained by polymerizing polyethylene oxide macromonomers, hydrophobic monomers, and cross-linking monomers under specific conditions as well as an oil-in-water emulsified composition characteristically using said emulsifying agent for emulsification.
The object of the present invention is to provide a new corona-core microgel emulsifying agent to be used to prepare an oil-in-water emulsified composition that manifests superior emulsification stability, stability over time, and low skin irritation, and is free of stickiness at the time of application, manifests dewy freshness, is free of powdery sensation and/or squeakiness, and is superior in durability of fragrance, as well as an oil-in-water emulsified composition emulsified with said emulsifying agent.

First claim

The invention claimed is:

1. A method of preparing an oil-in-water Pickering emulsion comprising
a corona-core microgel emulsifying agent in an amount of 0.1-3 wt % of the total amount of the oil-in-water Pickering emulsion,
an oil phase ingredient in an amount of 10-80 wt % of the total amount of the oil-in-water Pickering emulsion, and
a water phase ingredient,

wherein the corona-core microgel emulsifying agent is composed of a copolymer obtained by polymerizing polyethylene oxide macromononiers of the following formula (1), hydrophobic monomers of the following formula (2), and cross-linking monomers of the following formula (3) under the following conditions (A) and (B):
(A) a mole ratio of a feed mole amount of said polyethylene oxide macromonomers/a feed mole amount of the hydrophobic monomers is 1:10-1:250; and
(B) a feed amount of said cross-linking monomers is 0.1-1.5 wt % relative to a feed amount of said hydrophobic monomers;

R 1 denotes an alkyl having 1-3 carbon atoms, n is an integer 8-200, and X denotes H or

R 2 denotes an alkyl having 1-3 carbon atoms, and R 3 denotes an alkyl having 1-12 carbon atoms; and

R 4 and R 5 each independently denote an alkyl having 1-3 carbon atoms, and m is a number 0-2; and
wherein a core part is cross-linked with cross-linking monomers to prepare the microgel by using polymer fine particle polymerization method; the method comprising the steps of:
mixing and dispersing the corona-core microgel emulsifying agent in water or the water phase ingredient to form a dispersion;
adding the oil phase ingredient to the dispersion to form a mixture; and
emulsifying the mixture by stirring and applying shearing force.

2. The method of preparing an oil-in-water Pickering emulsion according to claim 1 , wherein the following conditions (C) and (D) are added for radical polymerization of polyethylene oxide macromonomers of the formula (1), hydrophobic monomers of the formula (2), and cross-linking monomers of the formula (3) in a water-ethanol mixed solvent to obtain the copolymer constituting the corona-core microgel emulsifying agent:
(C) the hydrophobic monomers of the formula (2) have a monomer composition of a mixture of one, two, or more methacrylic acid derivatives that have an alkyl having 1-8 carbon atoms; and
(D) the water-ethanol mixed solvent has a volume ratio at 20° C. of water:ethanol=90-30:10-70.

3. The method of preparing an oil-in-water Pickering emulsion according to claim 1 , wherein the oil-in-water Pickering emulsion comprises perfume as the oil phase ingredient in an amount of 0.5-40 wt % of the total amount of the oil-in-water Pickering emulsion.

4. The method of preparing an oil-in-water Picketing emulsion according to claim 2 , wherein the oil-in-water Pickering emulsion comprises perfume as the oil phase ingredient in an amount of 0.5-40 wt % of the total amount of the oil-in-water Pickering emulsion.

Assignees

• Shiseido Co Ltd

Inventors

• Sugiyama Yuki
• Sato Tomoko
• Shoji Ken

Classifications

• A61Q17/04

  Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations · CPC title

• A61K2800/95

  Involves in-situ formation or cross-linking of polymers · CPC title

• C08L33/10

  Homopolymers or copolymers of methacrylic acid esters · CPC title

• C08F220/14

  Methyl esters {, e.g. methyl (meth)acrylate} · CPC title

• B01J13/0065

  containing an organic phase · CPC title