Auto-injector

Patent metadata

Field	Value
Publication number	US-9539392-B2
Application number	US-201113994883-A
Country	US
Kind code	B2
Filing date	Dec 21, 2011
Priority date	Dec 21, 2010
Publication date	Jan 10, 2017
Grant date	Jan 10, 2017

Abstract

The invention relates to a front-end device of an auto-injector (A) for administering a dose of a liquid medicament, comprising of a support sleeve with a first screw thread adapted to engage a housing of a back-end device of the auto-injector (A) to attach the front-end device to the back-end device and an outer sleeve mounted onto a support sleeve of the front-end device by a second screw thread, wherein the front-end device is adapted to receive a syringe with an injection needle and a barrel containing the dose of the medicament and wherein the direction of rotation of the first screw thread is opposite to the direction of rotation of the second screw thread.

First claim

The invention claimed is:

1. A front-end device of an auto-injector (A) for administering a dose of a liquid medicament, comprising
a support sleeve with a first screw thread adapted to engage a housing of a back-end device of the auto-injector (A) to attach the front-end device to the back-end device and
an outer sleeve mounted onto a support sleeve of the front-end device by a second screw thread,
wherein the front-end device is adapted to receive a syringe with an injection needle and a barrel containing the dose of the medicament and wherein the direction of rotation of the first screw thread is opposite to the direction of rotation of the second screw thread, and
wherein a support collar separates the first screw thread from the second screw thread and a latch formed to the outer sleeve is arranged to latch to the support collar of the support sleeve to initially prevent a relative rotation between the outer sleeve and the support sleeve.

2. The front-end device according to claim 1 , wherein a syringe retainer adapted to receive the pre-filled syringe is slidably arranged with respect to the support sleeve between a first position (I) with the needle covered inside the support sleeve and a second position (II) with the needle exposed for injection, wherein the outer sleeve is arranged to abut against an assembly lock that comprises a second inward projection arranged to latch to a first flange of the syringe retainer to prevent an axial translation of the syringe retainer in the first position (I) towards the second position (II).

3. The front-end device according to claim 2 , wherein an annular rib is formed to the support sleeve to limit the axial translation of the syringe retainer in the proximal direction (P) so as to limit a maximal penetration depth of the injection needle.

4. The front-end device according to claim 1 , wherein a drive dog is slidably mounted to the support collar and is arranged to abut against the latch, wherein the drive dog is arranged to be engaged by the housing of the back-end device when attached to the support sleeve via the first screw thread and wherein the latch is adapted to be translated by the drive dog engaged by the housing to disengage from the support collar.

5. The front-end device according to claim 1 , wherein the outer sleeve is connected to at least one clamp arm adapted to clamp to a needle cap covering the injection needle.

6. The front-end device according to claim 5 , wherein the clamp arm is biased by a clamp spring radially inwards to retain the needle cap within the outer sleeve when the outer sleeve is detached from the support sleeve.

7. The front-end device according to claim 1 , wherein a needle shroud adapted to rest on the skin of a patient is slidably arranged with respect to the support sleeve, wherein the needle shroud comprises an extension arm adapted to communicate an axial displacement of the needle shroud to the back-end device of the auto-injector (A).

8. An auto-injector (A) for administering a dose of a liquid medicament, comprising:
a substantially tubular and reusable front-end device comprising:
a support sleeve with a first screw thread adapted to engage a housing of a back-end device of the auto-injector (A) to attach the front-end device to the back-end device and
an outer sleeve mounted onto a support sleeve of the front-end device by a second screw thread,
wherein the front-end device is adapted to receive a syringe with an injection needle and a barrel containing the dose of the medicament and wherein the direction of rotation of the first screw thread is opposite to the direction of rotation of the second screw thread, and
wherein a support collar separates the first screw thread from the second screw thread and a latch formed to the outer sleeve is arranged to latch to the support collar of the support sleeve to initially prevent a relative rotation between the outer sleeve and the support sleeve; and

a reusable back-end device comprising:
a housing,
a plunger connected to or adapted to engage a stopper providing a fluid tight seal for a distal end of the barrel,
a motor for displacing the plunger,

wherein the front-end device is attached to the housing via the first screw thread and the outer sleeve is mounted onto the support sleeve of the front-end device by a second screw thread, wherein the direction of rotation of the first screw thread is opposite to the direction of rotation of the second screw thread.

9. The auto-injector (A) according to claim 8 , wherein the outer sleeve is arranged to abut against an assembly lock that comprises a second inward projection arranged to latch to a first flange of the syringe retainer to prevent an axial translation of the syringe retainer in the first position (I) towards the second position (II), wherein the outer sleeve is arranged to release the assembly lock upon removal of the outer sleeve from the support sleeve, wherein, upon release, the assembly lock is capable of locking the support sleeve to the housing so as to prevent a relative rotation between the support sleeve and the housing.

10. The auto-injector (A) according to claim 8 , wherein the assembly lock comprises a first locking pin and a second locking pin, wherein the first locking pin protrudes into a first orifice formed into the support sleeve and the second locking pin protrudes through a second orifice formed into the support sleeve and into a third orifice formed into the housing to prevent the relative rotation between the support sleeve and the housing.

11. The auto-injector (A) according to claim 8 , wherein a needle shroud adapted to rest on the skin of a patient is slidably arranged with respect to the support sleeve, wherein an interlock switch is arranged within the back-end device capable of detecting an axial displacement of the needle shroud.

12. The auto-injector (A) according to claim 8 , wherein the back-end device comprises a sensor unit for detecting actual parameters of the injection, a memory unit for storing user related data and/or specification parameters and a means to provide a visual, acoustic and/or haptic feedback to the user of the auto-injector (A).

13. The auto-injector (A) according to claim 8 , wherein the back-end device further comprises an encoder sensor capable of determining the position of the plunger.

Assignees

• Jennings Douglas
• Kemp Thomas
• Ekman Matthew
• Sanofi Aventis Deutschland

Inventors

• Jennings Douglas
• Kemp Thomas
• Ekman Matthew

Classifications

• A61M2005/208

  Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin · CPC title

• A61M5/3204

  Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices · CPC title

• A61M2005/2488

  via rotation, e.g. threads or bayonet · CPC title

• A61M5/20 Primary

  Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically (A61M5/142 {, A61M5/46} take precedence; {hypodermic projectiles F42B12/54}) · CPC title

• A61M5/24

  Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic {(ampoules or carpules A61J1/06)} · CPC title