Prevention and treatment of thromboembolic disorders

US9539218B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9539218-B2
Application numberUS-88321806-A
CountryUS
Kind codeB2
Filing dateJan 19, 2006
Priority dateJan 31, 2005
Publication dateJan 10, 2017
Grant dateJan 10, 2017

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to the field of blood coagulation, more specifically it relates to a method of treating a thromboembolic disorder by administering once daily a direct factor Xa inhibitor in oral dosage form to a patient in need thereof, wherein the factor Xa inhibitor has a plasma concentration half life indicative of a bid or tid administration interval, e.g. of 10 hours or less.

First claim

Opening claim text (preview).

We claim: 1. A method of treating a thromboembolic disorder comprising administering a direct factor Xa inhibitor that is 5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide no more than once daily for at least five consecutive days in a rapid-release tablet to a patient in need thereof, wherein the thromboembolic disorder is selected from the group consisting of pulmonary embolisms, deep vein thromboses, and stroke. 2. The method of claim 1 , wherein the thromboembolic disorder is pulmonary embolisms. 3. The method of claim 1 , wherein the thromboembolic disorder is deep vein thromboses. 4. The method of claim 1 , wherein the thromboembolic disorder is stroke.

Assignees

Inventors

Classifications

  • Drugs for disorders of the blood or the extracellular fluid · CPC title

  • for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis · CPC title

  • Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors · CPC title

  • Drugs for disorders of the cardiovascular system · CPC title

  • Vasodilators for multiple indications · CPC title

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Frequently asked questions

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What does patent US9539218B2 cover?
The present invention relates to the field of blood coagulation, more specifically it relates to a method of treating a thromboembolic disorder by administering once daily a direct factor Xa inhibitor in oral dosage form to a patient in need thereof, wherein the factor Xa inhibitor has a plasma concentration half life indicative of a bid or tid administration interval, e.g. of 10 hours or less.
Who is the assignee on this patent?
Misselwitz Frank, Kubitza Dagmar, Park Son-Mi, and 2 more
What technology area does this patent fall under?
Primary CPC classification A61K31/5377. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jan 10 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).