Methods for detecting vitamin D metabolites by mass spectrometry
US-9244084-B2 · Jan 26, 2016 · US
Methods for detecting vitamin D metabolites by mass spectrometry
US9529004B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9529004-B2 |
| Application number | US-201615005801-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 25, 2016 |
| Priority date | Apr 6, 2005 |
| Publication date | Dec 27, 2016 |
| Grant date | Dec 27, 2016 |
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Abstract
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Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally are directed to ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay.
First claim
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What is claimed: 1. A method for determining the amount of a vitamin D metabolite in a sample by tandem mass spectrometry, comprising: (a) ionizing the vitamin D metabolite to generate a precursor ion; (b) generating one or more fragment ions from the precursor ion having a mass-to-charge ratio of 251.30±0.5, 211.35±0.5, 209.20±0.5, or 179.10±0.5; (c) detecting the amount of one or more of the ions generated in step (b) and relating the detected ions to the amount of the vitam…
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Electricity · mapped topic
Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
- G01N33/82Primary
Physics · mapped topic
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- What does patent US9529004B2 cover?
- Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally are directed to ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitami…
- Who is the assignee on this patent?
- Quest Diagnostics Invest Inc
- What technology area does this patent fall under?
- Primary CPC classification G01N33/82. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Dec 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).