Visual prosthesis for control of spatiotemporal interactions

Patent metadata

Field	Value
Publication number	US-9526888-B2
Application number	US-201314133274-A
Country	US
Kind code	B2
Filing date	Dec 18, 2013
Priority date	Jun 12, 2008
Publication date	Dec 27, 2016
Grant date	Dec 27, 2016

Abstract

In a visual prosthesis or other neural stimulator it is advantageous to provide non-overlapping pulses in order to provide independent control of brightness from different electrodes. Non-overlapping pulses on geographically close electrodes avoid electric-field interaction which leads to brightness summation or changes in the shape and area of percepts. It is advantageous to apply pulses to nearby electrodes in a way that the currents do not overlap in time at all. ‘Nearby’ is defined as within a few millimeters of each other. The same parameters that provide independent control of brightness also produce spatial patterns that the subjects' report as being similar to the sum of individual electrode phosphenes. Simultaneous stimulation of multiple electrodes can sometimes produce physical sensation or discomfort in the eye. Time-shifting the pulses cab also be used to reduce the physical sensations felt by the patient.

First claim

What is claimed is:

1. A neural stimulator comprising:
a first set of electrodes suitable to stimulate neural tissue;
a second set of electrodes suitable to stimulate neural tissue close enough to the first set of stimulating electrodes to cause electric field interactions at currents between 20 and 425 microamperes;
a signal generator coupled to the first set of electrodes generating a first set of suprathreshold stimulation pulses suitable to induce a first set of percepts; and
the signal generator coupled to the second set of electrodes generating a second set of suprathreshold stimulation pulses suitable to induce a second set of percepts, wherein the second set of stimulation pulses are phase shifted from the first set of stimulation pulses to minimize electrical field interactions between the first set of precepts and the second set of percepts.

2. The neural stimulator according to claim 1 , wherein the first set of electrodes is within 3 millimeters of the second set of electrodes.

3. The neural stimulator according to claim 1 , wherein the second set of stimulation pulses are non-overlapping with the first set of stimulation pulses.

4. The neural stimulator according to claim 3 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is greater than 0.225 milliseconds.

5. The neural stimulator according to claim 3 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is greater than 3 milliseconds.

6. The neural stimulator according to claim 3 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is less than 5 milliseconds.

7. The neural stimulator according to claim 3 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is sufficient to avoid amplitude summation.

8. The neural stimulator according to claim 3 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is sufficient to avoid area summation.

9. The neural stimulator according to claim 3 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is sufficient to avoid stimulation on a return electrode.

10. A visual prosthesis stimulating the perception of formed vision comprising:
a first set of electrodes suitable to stimulate visual neurons;
a second set of electrodes suitable to stimulate visual neurons close enough to the first set of electrodes to cause electric field interactions at currents between 20 and 425 microamperes;
a signal generator coupled to the first set of electrodes generating a first set of stimulation pulses suitable to stimulate a first set of visual percepts; and
the signal generator coupled to the second set of electrodes generating a second set of stimulation pulses to stimulate a second set of visual percepts;
wherein the second set of stimulation pulses are phase shifted from the first set of stimulation pulses to avoid electrical field interactions between the first set of visual precepts and the second set of visual percepts.

11. The visual prosthesis according to claim 10 , wherein the first set of electrodes is within 3 millimeters of the second set of electrodes.

12. The visual prosthesis according to claim 10 , wherein the second set of stimulation pulses are non-overlapping with the first set of stimulation pulses.

13. The visual prosthesis according to claim 12 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is greater than 0.225 milliseconds.

14. The visual prosthesis according to claim 12 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is greater than 3 milliseconds.

15. The visual prosthesis according to claim 12 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is less than 5 milliseconds.

16. The visual prosthesis according to claim 12 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is sufficient to avoid brightness summation.

17. The visual prosthesis according to claim 12 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is sufficient to avoid area summation.

18. The visual prosthesis according to claim 12 , wherein an inter-phase delay between the first set of stimulation pulses and the second set of stimulation pulses is sufficient to avoid non-visual sensations.

Assignees

• Second Sight Medical Products Inc

Inventors

• Horsager Alan M
• Mcmahon Matthew J
• Greenberg Robert J

Classifications

• A61N1/36046

  of the eye · CPC title

• A61N1/0543 Primary

  Retinal electrodes · CPC title