Medical balloons and methods of making the same

Patent metadata

Field	Value
Publication number	US-9526814-B2
Application number	US-35539206-A
Country	US
Kind code	B2
Filing date	Feb 16, 2006
Priority date	Feb 16, 2006
Publication date	Dec 27, 2016
Grant date	Dec 27, 2016

Abstract

Medical balloons are provided that have enhanced properties, such as enhanced puncture and scratch resistance.

First claim

What is claimed is:

1. A medical balloon, comprising:
a balloon wall having a base polymer system comprising a base polymer material with an integral modified region including a region of crosslinked base polymer material adjacent the base polymer material and a carbonized region of base polymer material adjacent the crosslinked region, the crosslinked region is thicker than the carbonized region, the integral modified region having a surface with a fractured surface morphology such that non-fractured islands defined by fracture lines in the surface and said non-fractured islands have an area not more than about 20 μm 2 .

2. The medical balloon of claim 1 , wherein the carbonized region includes diamond-like material.

3. The medical balloon of claim 1 , wherein the carbonized region includes graphitic material.

4. The medical balloon of claim 1 , wherein the crosslinked region is directly bonded to the carbonized base polymer material and to unmodified base polymer material.

5. The medical balloon of claim 1 , including an oxidized region, the oxidized region being directly bonded to the carbonized material and exposed to atmosphere.

6. The medical balloon of claim 1 , wherein the modified region extends from an exposed surface of the base polymer system.

7. The medical balloon of claim 1 , wherein the modulus of elasticity of the base polymer system is within about +/−10% of the base polymer system without the modified region.

8. The medical balloon of claim 1 , wherein the thickness of the modified region is about 10 to about 200 nm.

9. The medial balloon of claim 1 , wherein the modified region is about 1% or less of the overall thickness of the base polymer system.

10. The medial balloon of claim 1 , wherein a, hardness coefficient of the carbonized base polymer material is about 500 Vickers Hardness (kgf/mm 2 ) or more.

11. The medical balloon of claim 1 , wherein the base polymer system carries a therapeutic agent.

12. The medical balloon of claim 11 , wherein the fracture lines have a width of less than about 10 μm and act as a reservoir and comprise the therapeutic agent.

13. The medical balloon of claim 1 , wherein the base polymer system includes coextruded polymer layers.

14. The balloon of claim 1 , wherein a compliancy of the balloon is less than 10 percent of an initial diameter of the balloon between an internal pressure from about 2 bar to about 15 bar.

15. A balloon catheter, comprising:
a balloon wall having a base polymer system comprising a base polymer material with an integral modified region including a region of crosslinked of base polymer material adjacent the base polymer material and a carbonized region of base polymer material adjacent the crosslinked region, the crosslinked region is thicker than the carbonized region, the integral modified region having a surface with a fractured surface morphology such that non-fractured islands defined by fracture lines in the surface and said non-fractured islands have an area not more than about 20 μm 2 .

16. The balloon catheter of claim 15 , wherein the balloon catheter is sized for use in the vascular system.

17. The balloon catheter of claim 16 , wherein the balloon catheter is sized for use in the coronary arteries.

18. The balloon catheter of claim 15 , wherein the balloon catheter includes a stent positioned over the balloon.

19. A medical device, comprising:
a base polymer system including coextruded polymers, the base polymer system including an interface of the coextruded polymers, the base polymer system comprising a base polymer material, the base polymer system having an integral modified region including a crosslinked region of base polymer material adjacent the base polymer material and a carbonized region of base polymer material adjacent the crosslinked region, the crosslinked region is thicker than the carbonized region, the integral modified region having a surface with a fractured surface morphology such that non-fractured islands defined by fracture lines in the surface and said non-fractured islands have an area not more than about 20 μm 2 .

20. The medical device of claim 19 , wherein the modified region includes an interface of the coextruded polymers.

21. The medical device of claim 19 , wherein the medical device is a medical balloon.

22. The device of claim 21 , including a stent about the medical balloon.

23. The device of claim 19 , wherein the polymer system carries a therapeutic agent.

24. A medical balloon, comprising:
a balloon wall having a base polymer system comprising a base polymer material, the base polymer system having an integral modified region including a crosslinked region of base polymer material adjacent the base polymer material and a carbonized region of base polymer material adjacent the crosslinked region, the crosslinked region is thicker than the carbonized region, the integral modified region having a surface with a fractured surface morphology formed by a plurality of fracture lines, the fracture lines having a width of less than 10 μm.

25. The medical balloon of claim 24 , wherein the carbonized region includes diamond-like material.

26. The medical balloon of claim 24 , wherein the carbonized region includes graphitic material.

27. A medical balloon, comprising:
a balloon wall having a base polymer system comprising a base polymer material with an integral modified region including a crosslinked region of base polymer material adjacent the base polymer material and a carbonized region of base polymer material adjacent the crosslinked region, the crosslinked region is thicker than the carbonized region, the integral modified region having a surface with a fractured surface morphology such that non-fractured islands defined by fracture lines, said fracture lines have a width of less than 10 μm in the surface and said non-fractured islands have an area not more than about 20 μm 2 , and said fracture lines act as a reservoir and lines comprise a therapeutic agent.

28. The medical balloon of claim 27 wherein said fracture lines have a width of not more than about 0.5 μm.

Assignees

• Weber Jan
• Atanasoska Liliana
• Kondyurin Alexey
• Boston Scient Scimed Inc

Inventors

• Weber Jan
• Atanasoska Liliana
• Kondyurin Alexey

Classifications

• A61L31/084 Primary

  Carbon; Graphite · CPC title

• A61L27/303

  Carbon · CPC title