Pharmaceutical combination and use thereof
US-2024189341-A1 · Jun 13, 2024 · US
US9526778B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9526778-B2 |
| Application number | US-200913377070-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 15, 2009 |
| Priority date | Jun 15, 2009 |
| Publication date | Dec 27, 2016 |
| Grant date | Dec 27, 2016 |
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The invention relates to compositions and vaccines that include a mutated Bordetella strain for treating or preventing an influenza infection in a mammal. In addition, the invention further provides methods for protecting a mammal against infection by influenza and/or eliciting an immune response against an influenza virus in a mammal using the composition or vaccine.
Opening claim text (preview).
What is claimed: 1. A method of lessening the severity of lung immunopathology due to infection with influenza A virus in a mammalian subject who is at increased risk of developing the infection, said method comprising the step of administering to the subject a sufficient amount of a live attenuated, mutated Bordetella pertussis strain, wherein the strain comprises a mutated pertussis toxin(ptx) gene, a deleted or mutated dermonecrotic (dnt) gene, and a heterologous ampG gene, an…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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