Method of inhibiting C-KIT kinase

US9526731B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9526731-B2
Application numberUS-201414563126-A
CountryUS
Kind codeB2
Filing dateDec 8, 2014
Priority dateApr 20, 2006
Publication dateDec 27, 2016
Grant dateDec 27, 2016

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a compound of the present invention: or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof. The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.

First claim

Opening claim text (preview).

We claim: 1. A method of treating C-KIT related malignant myeloma, said method comprising inhibiting the kinase activity of C-KIT by administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising

Assignees

Inventors

Classifications

  • containing three or more hetero rings · CPC title

  • containing three or more hetero rings · CPC title

  • containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone · CPC title

  • Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin · CPC title

  • Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca · CPC title

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Frequently asked questions

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What does patent US9526731B2 cover?
A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a compound of the present invention: or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof. The present invention is …
Who is the assignee on this patent?
Janssen Pharmaceutica Nv
What technology area does this patent fall under?
Primary CPC classification A61K31/5377. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Dec 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).