Apparatus and methods for integrated sample preparation, reaction and detection
US-2018318838-A1 · Nov 8, 2018 · US
US9522367B1 · US · B1
| Field | Value |
|---|---|
| Publication number | US-9522367-B1 |
| Application number | US-201313751256-A |
| Country | US |
| Kind code | B1 |
| Filing date | Jan 28, 2013 |
| Priority date | Apr 27, 2011 |
| Publication date | Dec 20, 2016 |
| Grant date | Dec 20, 2016 |
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One or more embodiments relate to systems and methods for mixing of two or more fluids using a multi-chamber manifold. One or more embodiments relate to optimal mixing.
Opening claim text (preview).
The invention claimed is: 1. A mixing chamber comprising: (a) a body, the body having first and second body ends, an exterior wall with an interior having first and second chambers, and a plurality of inputs and at least one output; (b) the first chamber and second chamber being fluidly connected to each other; (c) a dividing structure that separates the first and second chambers, the dividing structure including a longitudinally extending plate having first and second side edges that each connect to the chamber exterior wall, first and second plate end portions, one said end portion connecting to the first body end, a transverse plate connected to the chamber exterior wall and to the second end portion of the longitudinal plate at a position spaced in between the first and second body ends; (d) the plurality of inputs entering the first chamber and the plurality of outputs exiting from the second chamber; and (e) the plurality of inputs being directed toward each other. 2. The mixing chamber of claim 1 , wherein the inputs are angled towards each other. 3. The mixing chamber of claim 2 , wherein the angle is selected from the group consisting of 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 14, 15, 16, 18, 20, 22, 24, 25, 26, 28, 30, 32, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 86, 87, 88, 89, and 90 degrees relative to a perpendicular from the exterior wall of the chamber. 4. A mixing chamber comprising: (a) an elongated body having an upstream end portion and a downstream end portion and a wall surrounding an interior; (b) the interior having a dividing structure that divides the interior into primary and secondary chambers; (c) the dividing structure including a transverse plate that connects to the body wall at a position in between the upstream and downstream end portions, the plate extending over only a part of the cross section of the housing; (d) the dividing structure including a longitudinal plate having plate edges and plate end portions, said edges connecting to the body wall, one said end portion connecting to said upstream end portion, wherein said longitudinal plate extends longitudinally from one end portion of the housing a partial distance of the housing length and connecting with the transverse plate at a said plate end portion; (e) a first mixing chamber formed by the transverse plate, the longitudinal plate, and a portion of the body wall, the first mixing chamber extending only a partial distance along the length of the body; (f) a second mixing chamber that is longer than the first mixing chamber, the second mixing chamber having a portion that contacts the longitudinal plate; (g) multiple inlets through the body wall that enable fluid to be added to the first mixing chamber; (h) one or more outlets in the body wall that enable fluid discharge from the second chamber; and (i) a flow path gate that extends through the dividing structure and that enables fluid flow from the first chamber to the second chamber. 5. The mixing chamber of claim 4 wherein some of the inlets are on opposing sides of the gate. 6. The mixing chamber of claim 4 wherein the gate is in between two of said inlets. 7. The mixing chamber of claim 4 wherein the transverse plate is positioned in the middle of the body. 8. The mixing chamber of claim 4 wherein there are outlets on the upstream side of the transverse plate. 9. The mixing chamber of claim 5 wherein some of the outlets are in between the transverse plate and one of the inlets. 10. The mixing chamber of claim 1 wherein one or more of the outlets are in between the transverse plate and the gate. 11. The mixing chamber of claim 1 wherein there are one or more baffles next to the gate. 12. The mixing chamber of claim 4 wherein all of the inlets are between the transverse plate and the first end portion of the body. 13. The mixing chamber of claim 4 wherein some of the inlets include an elbow shaped fitting. 14. The mixing chamber of claim 5 wherein some of the inlets include an elbow shaped fitting. 15. The mixing chamber of claim 4 wherein a majority of the inlets are in between the transverse plate and the second end portion of the body. 16. The mixing chamber of claim 11 wherein one or more baffles extend above the gate and one or more baffles extend below the plate. 17. The mixing chamber of claim 4 wherein at least one of the elbow shaped fittings discharges flow toward the gate. 18. The mixing chamber of claim 4 wherein multiple of the elbow shaped fittings discharge flow toward the gate.
Operations & Transport · mapped topic
Operations & Transport · mapped topic
Operations & Transport · mapped topic
characterised by the relative arrangement of the containers for feeding or mixing the components · CPC title
wherein the vortex is created by two or more jets introduced tangentially in separate mixing chambers or consecutively in the same mixing chamber · CPC title
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