Methods, compositions, and delivery systems for therapeutic skin treatments
US-2024390236-A1 · Nov 28, 2024 · US
US9522111B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9522111-B2 |
| Application number | US-201114365082-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 16, 2011 |
| Priority date | Dec 16, 2011 |
| Publication date | Dec 20, 2016 |
| Grant date | Dec 20, 2016 |
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Described herein are oral care compositions comprising an antibacterial agent and a dissolvable film comprising a pigment which provide a color change signal after a sufficient period of brushing, wherein the dentifrice base has water activity less than 0.78 and comprises anionic polymer in free or salt form 10-25% by weight of the dentifrice base, and anionic surfactant less than 3% by weight; together with methods of making and using the compositions.
Opening claim text (preview).
The invention claimed is: 1. An oral care composition comprising a dentifrice base; an antibacterial agent; and a dissolvable film comprising a pigment which provides a color change signal after a sufficient period of brushing, wherein the dentifrice base has a water activity less than 0.78 and comprises an anionic polymer in free or salt form in the amount of 10-25% by weight of the dentifrice base, and an anionic surfactant at an amount of less than 3% by weight; wherein the dissolvable film comprises, by dry weight of the film, 20-60% cellulose ethers selected from methyl cellulose, hydroxypropylmethyl cellulose, and mixtures thereof; 10-30% propylene glycol; 1-5% polysorbate 80; and 15-55% pigment. 2. The composition according to claim 1 wherein the anionic polymer is methyl vinyl ether/maleic anhydride co-polymer having a molecular weight (M.W.) of about 30,000 to about 1,000,000, optionally partially or fully in the form of an orally acceptable base addition salt. 3. The composition according to claim 1 further comprising an effective amount of fluoride. 4. The composition according to claim 1 wherein a 1″×1″ swatch of the film placed in water will not disintegrate and release active in water at room temperature in less than 5 minutes in the absence of agitation. 5. The composition according to claim 1 wherein the dissolvable film further comprises a starch. 6. The composition according to claim 1 wherein the dissolvable film is substantially dissolved after a period of greater than 30 seconds and less than 180 seconds of brushing, scrubbing or agitation in the presence of water. 7. The composition according to claim 1 further comprising a humectant selected from: glycerin, sorbitol, polyethylene glycol, xylitol, and a combination of two or more thereof. 8. The composition according to claim 1 further comprising an abrasive. 9. A method of cleaning the teeth comprising brushing with a composition according to claim 1 , wherein brushing is continued until the film disintegrates and the pigment provides a color signal to the user of adequate brushing.
anionic · CPC title
containing more than one hydroxy group · CPC title
Antimicrobial preparations · CPC title
with oxygen as the only hetero atom · CPC title
Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title
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