Preparation of n-monofluoroalkyl compounds
US-2016376265-A1 · Dec 29, 2016 · US
US9518074B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9518074-B2 |
| Application number | US-201514986238-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 31, 2015 |
| Priority date | Mar 10, 2011 |
| Publication date | Dec 13, 2016 |
| Grant date | Dec 13, 2016 |
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A method for producing a fluorine-containing substituted compound, the method including: introducing an organofluorine compound and an organolithium compound into a microreactor provided with a flow path capable of mixing a plurality of liquids, to thereby obtain a reaction product; and introducing, into the microreactor, the reaction product and an electrophile exhibiting electrophilic effect on the reaction product, to thereby obtain a fluorine-containing substituted compound.
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What is claimed is: 1. A fluorine-containing substituted compound represented by the following general formula (4): wherein, in the general formula (4) R 5 to R 7 may be the same as or different from each other, each represent an aliphatic group having 1 to 9 carbon atoms which may have a substituent, an aromatic group having 3 to 19 carbon atoms which may have a substituent, or a heterocyclic group having 3 to 19 carbon atoms which may have a substituent; X represents a halogen atom other than a fluorine atom; and j, k, l and m satisfy the relation 2j+1=k+l+m, where j is an integer of 1 to 20, k is 0 and m is an integer of 0 or more, and l is an integer of 1 or more.
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