Process for preparing [(3-hydroxypyridine-2-carbonyl)amino]alkanoic acids, esters and amides
US-2015361043-A1 · Dec 17, 2015 · US
US9518019B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9518019-B2 |
| Application number | US-201615040577-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 10, 2016 |
| Priority date | Dec 13, 2012 |
| Publication date | Dec 13, 2016 |
| Grant date | Dec 13, 2016 |
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4-Amino-5-fluoro-3-chloro-6-(substituted)picolinates are prepared from trifluoroacetic acid, p-methoxyaniline, a C 1 -C 4 alkyl propiolate and a substituted methylene amine by a series of steps.
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What is claimed is: 1. A compound of Formula E wherein R 1 represents C 1 -C 4 alkyl, cyclopropyl, C 2 -C 4 alkenyl or phenyl substituted with from 1 to 4 substituents independently selected from halogen, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy or C 1 -C 4 haloalkoxy, and R 2 represents C 1 -C 4 alkyl. 2. A compound of Formula G wherein R 1 represents C 1 -C 4 alkyl, cyclopropyl, C 2 -C 4 alkenyl or phenyl substituted with from 1 to 4 substituents independently selected from halogen, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 1 -C 4 alkoxy or C 1 -C 4 haloalkoxy, and R 2 represents C 1 -C 4 alkyl.
Processes of preparation · CPC title
being acyclic · CPC title
Acids; Esters · CPC title
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