2-cycloalkyl resorcinol cannabinergic ligands
US-9517989-B2 · Dec 13, 2016 · US
Antagonists of the toll-like receptor 1/2 complex
US9517993B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9517993-B2 |
| Application number | US-201314417676-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 29, 2013 |
| Priority date | Jul 29, 2012 |
| Publication date | Dec 13, 2016 |
| Grant date | Dec 13, 2016 |
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Abstract
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Provided are compounds, compositions and methods for treating Toll-like receptor 1/2 complex (TLRI/2) related inflammatory disorders. Small molecules, based on the benzotropolone scaffold, capable of influencing downstream signaling are disclosed as well as methods of making and modifying these molecules. Also provided are methods for treating a subject for a clinical condition associated with Toll-like receptor complex 1/2 activation, comprising administering to the subject an effective amount of a benzotropolone compound.
First claim
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What is claimed is: 1. A compound having the chemical structure: or a pharmaceutically acceptable salt thereof. 2. A compound having the chemical structure: or a pharmaceutically acceptable salt thereof. 3. A compound…
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Chemistry & Metallurgy · mapped topic
- C07C49/747Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9517993B2 cover?
- Provided are compounds, compositions and methods for treating Toll-like receptor 1/2 complex (TLRI/2) related inflammatory disorders. Small molecules, based on the benzotropolone scaffold, capable of influencing downstream signaling are disclosed as well as methods of making and modifying these molecules. Also provided are methods for treating a subject for a clinical condition associated with …
- Who is the assignee on this patent?
- Univ Colorado Regents
- What technology area does this patent fall under?
- Primary CPC classification C07C49/747. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Dec 13 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).