Method of delivering medical gases via a nasal cannula assembly with flow control passage communicating with a deformable reservoir

Patent metadata

Field	Value
Publication number	US-9517318-B2
Application number	US-201313930545-A
Country	US
Kind code	B2
Filing date	Jun 28, 2013
Priority date	Jun 28, 2013
Publication date	Dec 13, 2016
Grant date	Dec 13, 2016

Abstract

The invention concerns a nasal cannula assembly ( 10 ) adapted to deliver gases to a patient comprising a first compartment ( 1 ) and a second compartment ( 2 ) separated by a separation wall ( 6 ); a pair of nasal prongs ( 5 ) in fluid communication with the first compartment ( 1 ); the first compartment ( 1 ) comprising a first inlet ( 11 ) for introducing a first gas into said first compartment ( 1 ); the second compartment ( 2 ) comprising a second inlet ( 2 ) for introducing a second gas into said second compartment ( 2 ); and the separation wall ( 6 ) comprising at least one flow restriction element ( 35 ) for controlling the passage of gas from the second compartment ( 2 ) to the first compartment ( 1 ).

First claim

The invention claimed is:

1. A method for treating pulmonary vasoconstriction in a patient, comprising:
a) providing a nasal cannula assembly ( 10 ) adapted to deliver gases to a patient, the nasal cannula assembly ( 10 ) comprising:
A) a hollow body ( 4 ) configured to be capable of acting as a gas conduct or a gas manifold and comprising an internal chamber ( 7 ) defining a first compartment ( 1 ),
B) the first compartment ( 1 ) and a second compartment ( 2 ) separated by a separation wall ( 6 ),
C) a pair of nasal prongs ( 5 ) in fluid communication with the first compartment ( 1 ),
D) the first compartment ( 1 ) comprising a first inlet ( 11 ) forming a side gases entry in fluid communication with a gas transport conduct and configured to conduct a first gas into said first compartment ( 1 ),

E) the second compartment ( 2 ) having a fully inflated internal volume for a gas of about 0.5 to 5 ml, the second compartment ( 2 ) comprising,
a second inlet ( 12 ) configured to conduct a second gas into said second compartment ( 2 ), and
a deformable wall ( 14 ) forming a part of a boundary between the second compartment ( 2 ) and a room atmosphere such that the compliance of the second compartment ( 2 ) is not less than 5 ml/cm H 2 O while filling but is less than 0.1 ml/cm H 2 O once the second compartment ( 2 ) is full,

F) the separation wall ( 6 ) comprising two flow restriction channels ( 35 )
having a rounded edge at an entrance from second compartment ( 2 ) and
having a reentrant aperture at an exit into the first compartment ( 1 ) and
which are oriented and arranged in the separation wall ( 6 ) directly opposite the pair of nasal prongs ( 5 ) to thereby be capable of
a. permitting a passage of gas from the second compartment ( 2 ) to the first compartment ( 1 ) in a reduced pressure state during an inhalation phase and
b. preventing a majority of flow of the second gas from the second compartment ( 2 ) to the first compartment ( 1 ) in a higher pressure state, during an exhalation phase, relative to the passage of gas during the reduced pressure state, during an inhalation phase, such that during the higher pressure state exhalation phase the majority of flow of the second gas entering the second compartment ( 2 ) from the second inlet ( 12 ) is retained in the second compartment ( 2 ) causing the deformable wall ( 14 ) to deform and increase the volume of the second compartment ( 2 ) by at least 50% volume, as compared to the second compartment ( 2 ) volume at the end of the previous reduced pressure state inhalation phase,

b) providing a therapeutically-effective amount of a NO-containing gas to said patient through said nasal cannula assembly ( 10 ) for inhalation to thereby reduce the pulmonary vasoconstriction in the patient.

2. The method for treating pulmonary vasoconstriction in a patient according to claim 1 , further comprising one or more orifices ( 13 ) in the first compartment ( 1 ) defining a fluid communication from an internal chamber ( 7 ) and an external atmosphere.

Assignees

• L'Air Liquide Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude

Inventors

• Martin Andrew

Classifications

• A61M16/0672 Primary

  Nasal cannula assemblies for oxygen therapy · CPC title

• A61M16/0666

  Nasal cannulas or tubing (devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02) · CPC title

• A61M2202/0275

  Nitric oxide [NO] · CPC title

• A61M2202/0208

  Oxygen · CPC title

• A61M16/122

  with dilution · CPC title