Oral care composition with cross-linked polymer peroxide

Patent metadata

Field	Value
Publication number	US-9517194-B2
Application number	US-201514723139-A
Country	US
Kind code	B2
Filing date	May 27, 2015
Priority date	Aug 27, 2004
Publication date	Dec 13, 2016
Grant date	Dec 13, 2016

Abstract

Oral care compositions comprising:
(a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier.

In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising:
(a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

First claim

What is claimed is:

1. An oral care composition comprising:
(a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer;
(b) a whitening agent;
(c) an orally acceptable carrier;
wherein the peroxide complex comprises a cross-linked polyvinyl pyrrolidone-peroxide complex wherein the whitening agent comprises hydrogen peroxide, and wherein said carrier comprises a block copolymer of ethylene oxide and propylene oxide;
wherein the composition further comprises tetrasodium pyrophosphate and calcium pyrophosphate.

2. The composition of claim 1 , further comprising polyethylene glycol.

3. The composition of claim 1 , wherein the peroxide complex is present at a level of 0.5% to 40%.

4. The composition of claim 1 , wherein the peroxide complex is present at a level of 20% to 30%.

5. The composition of claim 1 , wherein the peroxide complex comprises a peroxide component at a level of 1% to 25%.

6. The composition of claim 1 , wherein the peroxide complex comprises a peroxide component at a level of 5% to 18%.

7. The composition of claim 1 , wherein the molar ratio of the peroxide component to the cross-linked polyvinyl pyrrolidone is about 1:1.

8. The composition of claim 2 , wherein the polyethylene glycol is selected from PEG-200, PEG-300, PEG-400, PEG-600 and PEG-2000.

9. The composition of claim 2 , wherein the polyethylene glycol comprises PEG-600.

Assignees

• Colgate Palmolive Co

Inventors

• Zaidel Lynette A
• Pan Guisheng
• Chopra Suman K
• Mandadi Prakasarao
• Prencipe Michael

Classifications

• A61K8/22

  Peroxides; Oxygen; Ozone · CPC title

• A61K8/49

  containing heterocyclic compounds · CPC title

• A61K8/90

  Block copolymers (A61K8/89 takes precedence) · CPC title

• A61K8/0208

  Tissues; Wipes; Patches · CPC title

• A61K8/24

  Phosphorous; Compounds thereof · CPC title