Use in ruminants of a food additive including a sweetener

Patent metadata

Field	Value
Publication number	US-9516892-B2
Application number	US-201314424918-A
Country	US
Kind code	B2
Filing date	Aug 29, 2013
Priority date	Aug 30, 2012
Publication date	Dec 13, 2016
Grant date	Dec 13, 2016

Abstract

The invention concerns the use of a food additive including a sweetener in the feed or the drink of a ruminant animal to reduce the impact of stressful conditions on intestinal mucosa quality.

First claim

The invention claimed is:

1. Method of reducing an impact of stressful conditions on intestinal mucosa quality of a ruminant animal, comprising:
administering a food additive in a feed or a drink of the ruminant animal so as to reduce the impact of the stressful conditions on the intestinal mucosa quality,
wherein the food additive comprises a sweetener and a potentiator.

2. Method according to claim 1 , wherein the food additive improves at least one of growth, permeability, absorption, and immune functions of the intestinal mucosa.

3. Method according to claim 1 , wherein the food additive is administered in case of at least one of heat stress, oxidative stress, and major feed changes, especially at weaning.

4. Method according to claim 1 , wherein the food additive is administered in at least one of a preventive way and in a curative way.

5. Method according to claim 4 , wherein, in a preventive way, the food additive improves intestinal mucosa quality.

6. Method according to claim 4 , wherein, in a curative way, the food additive limits degradation of intestinal mucosa quality.

7. Method according to claim 1 , wherein the food additive is administrated before the stressful conditions.

8. Method according to claim 1 , wherein the food additive is administrated during the stressful conditions.

9. Method according to claim 1 , wherein the food additive is administered to an un-weaned animal at a dose lower or equal to 400 grams of sweetener per ton of dehydrated milk replacer.

10. Method according to claim 1 , wherein the food additive is administered to a weaned animal at a dose lower or equal to 200 grams of sweetener per ton of feed as dry matter.

11. Method according to claim 1 , wherein the food additive is administered to a weaned animal at a dose lower or equal to 100 grams of sweetener per ton of drinking water.

12. Method according to claim 1 , wherein the food additive is administered to a weaned animal at a dose lower or equal to 150 grams of sweetener per ton of feed as dry matter.

13. Method according to claim 1 , wherein the food additive is administered to a weaned animal at a dose lower or equal to 75 grams of sweetener per ton of drinking water.

14. Method according to claim 1 , wherein the food additive is administered to a weaned animal at a dose lower or equal to 100 grams of sweetener per ton of feed as dry matter.

15. Method according to claim 1 , wherein the food additive is administered to a weaned animal at a dose lower or equal to 50 grams of sweetener per ton of drinking water.

16. Method according to claim 1 , wherein the sweetener is an intense sweetener.

17. Method according to claim 16 , wherein the sweetener comprises saccharin.

18. Method according to claim 16 , wherein the sweetener comprises at least one compound selected from the group consisting of sodium saccharin, calcium saccharin, aspartame, acesulfame K, stevioside and cyclamate.

19. Method according to claim 1 , wherein the potentiator is at least one compound selected from the group consisting of glycyrrhizin, ammonium glycyrrhizinate, potassium glycyrrhizinate, sodium glycyrrhizinate, thaumatin, kokumi, neohesperidin dihydrochalcone, ribotides and sodium glutamate.

20. Method according to claim 1 , wherein the food additive comprises from 0% to 20% by weight of potentiator(s).

21. Method according to claim 1 , wherein the animal is a calf.

Assignees

• Pancosma Sa
• Univ Liverpool
• Pancosma S A

Inventors

• Bravo David
• Shirazi-Beechey Soraya P

Classifications

• A23K50/10

  for ruminants · CPC title

• A61K31/428 Primary

  condensed with carbocyclic rings · CPC title

• A23K20/10

  Organic substances · CPC title

• A23K20/137 Primary

  containing two hetero atoms, of which at least one is nitrogen · CPC title

• A23K20/163

  Sugars; Polysaccharides · CPC title