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Polymorphisms in the PDE3A gene
US9512481B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9512481-B2 |
| Application number | US-201013395311-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 13, 2010 |
| Priority date | Sep 11, 2009 |
| Publication date | Dec 6, 2016 |
| Grant date | Dec 6, 2016 |
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Abstract
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Embodiments of the invention are directed to identifying or treating a patient that would benefit from phosphodiesterase inhibitor therapy.
First claim
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The invention claimed is: 1. A method for treating a human patient with heart failure comprising treating the patient with an effective amount of a PDE3A inhibitor after the patient is determined to be homozygous for an insertion of an ectotropic viral integration site-1 (Evi-1) binding site in the phosphodiesterase type 3A (PDE3A) gene promoter, wherein the Evi-1 binding site insertion is 85% identical to SEQ ID NO:2 and is located within 2000 nucleotides 5′ of the PDE3A gene tran…
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Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9512481B2 cover?
- Embodiments of the invention are directed to identifying or treating a patient that would benefit from phosphodiesterase inhibitor therapy.
- Who is the assignee on this patent?
- Sucharov Carmen, Bristow Michael, Taylor Matthew, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/6883. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Dec 06 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).