Methods and nucleic acid molecules for aav vector selection
US-2024417717-A1 · Dec 19, 2024 · US
US9512445B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9512445-B2 |
| Application number | US-78005110-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 14, 2010 |
| Priority date | Aug 31, 2009 |
| Publication date | Dec 6, 2016 |
| Grant date | Dec 6, 2016 |
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A humeral prosthetic head has a non-spherical articulation surface coupled with an intermediate component connecting the head and the humerus, the intermediate component connected to the epiphysis, metaphysis, or diaphysis, or to one or more additional components connected to the humerus. The intermediate portion provides for axial and angular offset of the head with respect to a connection to the humerus, using a curvilinear tapered engagement.
Opening claim text (preview).
What is claimed is: 1. A device for replacing a portion of a bone joint, comprising: a prosthetic head comprising an articulation surface having a shape of a semi-ellipsoid, and a bottom surface, wherein the bottom surface includes a taper feature for engagement with an engagement member connectable to the joint, the engagement member connectable to said prosthetic head and operable to maintain a proper orientation of said semi-ellipsoid shape of said articulation surface with respect to the joint. 2. The device of claim 1 , further including the engagement member. 3. The device of claim 2 , wherein the joint is a shoulder, and wherein said engagement member is sized and dimensioned to be engageable to bone of a humerus. 4. The device of claim 2 , wherein the joint is a shoulder, and wherein said engagement member is sized and dimensioned to be engageable upon a cut surface of a bone of a humerus. 5. The device of claim 2 , wherein said engagement member is sized and dimensioned to connect to the epiphysis or metaphysis of a bone adjacent to the joint. 6. The device of claim 2 , wherein said engagement member is configured to connect to a prosthetic stem associated within the diaphysis of a bone adjacent to the joint. 7. The device of claim 2 , wherein said engagement member is connectable to a prosthetic stem, the prosthetic stem connected to bone of the joint. 8. The device of claim 1 , further comprising a bone connecting member, said bone connecting member connectable to a bone of the joint, and taper means for connecting said bone connecting member to the engagement member. 9. The device of claim 1 , wherein said prosthetic head is a humeral head.
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