Library preparation methods and compositions and uses therefor
US-12065643-B2 · Aug 20, 2024 · US
US9512422B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9512422-B2 |
| Application number | US-201313787396-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 6, 2013 |
| Priority date | Feb 26, 2013 |
| Publication date | Dec 6, 2016 |
| Grant date | Dec 6, 2016 |
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Provided is an array including a solid support having a surface, the surface having a plurality of wells, the wells containing a gel material, the wells being separated from each other by interstitial regions on the surface, the interstitial regions segregating the gel material in each of the wells from the gel material in other wells of the plurality; and a library of target nucleic acids in the gel material, wherein the gel material in each of the wells comprises a single species of the target nucleic acids of the library. Methods for making and using the array are also provided.
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What is claimed is: 1. An array, comprising a solid support comprising a surface, the surface comprising a plurality of wells, the wells containing a gel material, the wells being separated from each other by interstitial regions on the surface, the interstitial regions segregating the gel material in each of the wells from the gel material in other wells of the plurality, wherein the volume of each of the wells is at most 1×10 4 μm 3 ; and a library of target nucleic acids in…
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