High Fidelity Restriction Endonucleases
US-2024352437-A1 · Oct 24, 2024 · US
Polypeptides having organophosphorous hydrolase activity
US9512413B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9512413-B2 |
| Application number | US-201314403949-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 31, 2013 |
| Priority date | May 31, 2012 |
| Publication date | Dec 6, 2016 |
| Grant date | Dec 6, 2016 |
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- Title
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- Abstract
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Abstract
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The present invention relates to isolated polypeptides having organophosphorous hydrolase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for removing an organophosphorous compound, comprising contacting the organophosphorous compound with a polypeptide having organophosphorous hydrolase activity and comprising an amino acid sequence having at least 90% sequence identity to the amino acid sequence of amino acids 12 to 314 of SEQ ID NO: 2 to thereby remove the organophosphorous compound. 2. The method of claim 1 , wherein the polypeptide has at least 94% sequence identity to the amino acid sequence of amino acids 12 to 314 of SEQ ID NO: 2. 3. The method of claim 1 , wherein the polypeptide has at least 95% sequence identity to the amino acid sequence of amino acids 12 to 314 of SEQ ID NO: 2. 4. The method of claim 1 , wherein the polypeptide has at least 96% sequence identity to the amino acid sequence of amino acids 12 to 314 of SEQ ID NO: 2. 5. The method of claim 1 , wherein the polypeptide has at least 97% sequence identity to the amino acid sequence of amino acids 12 to 314 of SEQ ID NO: 2. 6. The method of claim 1 , wherein the polypeptide has at least 98% sequence identity to the amino acid sequence of amino acids 12 to 314 of SEQ ID NO: 2. 7. The method of claim 1 , wherein the polypeptide has at least 99% sequence identity to the amino acid sequence of amino acids 12 to 314 of SEQ ID NO: 2. 8. The method of claim 1 , wherein the organophosphorous compound is a nerve gas, toxin or pesticide. 9. A method for decontaminating an area or a device contaminated with an organophosphorous compound, comprising contacting the area or device with a polypeptide having organophosphorous hydrolase activity and comprising an amino acid sequence having at least 90% sequence identity to the amino acid sequence of amino acids 12 to 314 of SEQ ID NO: 2 to thereby decontaminate the area or device. 10. The method of claim 9 , wherein the polypeptide has at least 99% sequence identity to the amino acid sequence of amino acids 12 to 314 of SEQ ID NO: 2. 11. The method of claim 9 , wherein the organophosphorous compound is a nerve gas, toxin or pesticide.
Assignees
Inventors
Classifications
Pesticides, e.g. insecticides, herbicides, fungicides or nematocides · CPC title
by biological methods, i.e. processes using enzymes or microorganisms · CPC title
Diisopropyl-fluorophosphatase (3.1.8.2) · CPC title
containing nitrogen or phosphorus · CPC title
- C12N9/16Primary
acting on ester bonds (3.1) · CPC title
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- What does patent US9512413B2 cover?
- The present invention relates to isolated polypeptides having organophosphorous hydrolase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
- Who is the assignee on this patent?
- Novozymes As
- What technology area does this patent fall under?
- Primary CPC classification C12N9/16. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Dec 06 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).