Therapeutic apparatus comprising a radiotherapy apparatus, a mechanical positioning system, and a magnetic resonance imaging system

Patent metadata

Field	Value
Publication number	US-9511242-B2
Application number	US-201113992793-A
Country	US
Kind code	B2
Filing date	Dec 2, 2011
Priority date	Dec 13, 2010
Publication date	Dec 6, 2016
Grant date	Dec 6, 2016

Abstract

A therapeutic apparatus ( 400, 500 ) comprising a radiotherapy apparatus ( 402 ), a mechanical positioning system, and a magnetic resonance imaging system ( 404 ). The radiotherapy apparatus comprises a radiotherapy source ( 408 ). The radiotherapy apparatus is adapted for rotating the radiotherapy source at least partially around a subject support. The therapeutic apparatus further comprises a memory containing machine executable instructions ( 468, 470, 472, 474, 476 ). Execution of the instructions causes a processor to repeatedly: acquire ( 100 ) the magnetic resonance data using the magnetic resonance imaging system; reconstruct ( 102 ) a magnetic resonance image ( 460 ) from the magnetic resonance data; register ( 104 ) a location ( 462 ) of the target zone in the magnetic resonance image; generate ( 106 ) radiotherapy control signals ( 464 ) in accordance with the location of the registered target zone; generate ( 108 ) mechanical positioning control signals ( 466 ) in accordance with the registered target zone and the radiotherapy control signals; and send ( 110 ) the radiotherapy control signals to the radiotherapy system and send ( 110 ) the mechanical positioning control signals to the mechanical positioning system.

First claim

The invention claimed is:

1. A therapeutic apparatus comprising:
a radiotherapy apparatus, the radiotherapy apparatus comprising:
a radiotherapy source for directing electromagnetic radiation into a target zone;
wherein the radiotherapy apparatus is adapted for rotating the radiotherapy source at least partially around a subject support,
wherein the radiotherapy apparatus is adapted for tilting the radiotherapy source with respect to an axis of rotation of the radiotherapy source;

a mechanical positioning system for positioning a subject support;
a magnetic resonance imaging system for acquiring magnetic resonance data from an imaging zone, the magnetic resonance imaging system comprising:
a magnet for generating a magnetic field within the imaging zone,
wherein the target zone is within the imaging zone,

a cylindrical collimator assembly, comprising:
a rotatable collimator member having a plurality of channels,
wherein the rotatable collimator member comprises a rotatable disk in which each of the plurality of channels are provided at different radial distances relative to a center of rotation of the rotatable disk;

a computer processor for controlling the therapeutic apparatus; and
a computer memory containing machine executable instructions, the executable instructions arranged for execution by the computer processor, wherein execution of the instructions causes the processor to repeatedly:
acquire the magnetic resonance data using the magnetic resonance imaging system;
reconstruct a magnetic resonance image from the magnetic resonance data;
register a location of the target zone in the magnetic resonance image;
generate radiotherapy control signals in accordance with the location of the registered target zone,
wherein the radiotherapy control signals cause the radiotherapy source to irradiate the target zone,
wherein the radiotherapy control signals cause an angular rotation of the rotatable collimator member and the angular rotation at least partially controls the location of a beam path of the radiotherapy source in the target zone;

generate mechanical positioning control signals in accordance with the registered target zone and the radiotherapy control signals, wherein the mechanical positioning control signals cause the mechanical positioning system to position the subject support; and

send the radiotherapy control signals to the radiotherapy system and send the mechanical positioning control signals to the mechanical positioning system.

2. The therapeutic apparatus of claim 1 , wherein the radiotherapy source comprises a first pencil beam collimator.

3. The therapeutic apparatus of claim 2 ,
wherein the cylindrical collimator assembly comprises a plurality of pencil beam collimators,
wherein the plurality of pencil beam collimators include the first pencil beam collimator,
wherein the cylindrical collimator assembly has a rotational axis,
wherein rotation of the cylindrical shaped collimator assembly causes a selected beam collimator chosen from the plurality of pencil beam collimators to align with the beam path.

4. The therapeutic apparatus of claim 3 , wherein the radiotherapy control signals cause the cylindrical collimator assembly to select the selected beam collimator.

5. The therapeutic apparatus of claim 3 , wherein the angular rotation of the rotatable collimator member is controlled as a function of time.

6. The therapeutic apparatus of claim 1 , wherein the radiotherapy control signals cause the radiotherapy system to perform one of,
adjusting a timing of the radiation source as a function of time,
adjusting an intensity of the radiation source as a function of time, and
controlling the rotating of the radiation as a function of time.

7. The therapeutic apparatus of claim 1 , wherein the mechanical positioning control signals cause the mechanical positioning system to adjust the position of the subject support as a function of time.

8. The therapeutic apparatus of claim 1 , wherein the location of the target zone is co-registered to the subject support, the radiotherapy apparatus, and the magnetic resonance imaging system.

9. The therapeutic apparatus of claim 1 , wherein the radiotherapy source comprises an adjustable beam collimator, wherein the radiotherapy control signals control the beam collimator.

10. The therapeutic apparatus of claim 1 , wherein the repeated execution of the machine executable instructions forms a closed control loop for directing the electromagnetic radiation into the target zone.

11. The therapeutic apparatus of claim 1 , wherein the cylindrical collimator assembly is adapted for tilting the rotatable collimator member with respect to an axis of rotation of the radiotherapy source.

12. A tangible computer-readable medium, in which a computer program including non-transitory computer instructions for execution by a processor, the computer instructions directing control of a therapeutic apparatus,
wherein the therapeutic apparatus comprises a radiotherapy apparatus for treating a target zone of a subject,
wherein the radiotherapy apparatus comprises a radiotherapy source for directing electromagnetic radiation into the target zone,
wherein the radiotherapy apparatus is adapted for tilting the radiotherapy source with respect to an axis of rotation of the radiotherapy source,
wherein the radiotherapy apparatus further comprises a cylindrical collimator assembly, the cylindrical collimator assembly comprising a rotatable collimator member, the rotatable collimator member comprising a plurality of channels, the rotatable collimator member comprising a rotatable disk in which the channels are provided at different radial distances relative to a center of rotation of the rotatable disk,
wherein the therapeutic apparatus further comprises a mechanical positioning system for positioning a subject support,
wherein the therapeutic apparatus further comprises a magnetic resonance imaging system for acquiring magnetic resonance data from an imaging zone,
wherein the target zone is within the imaging zone,
wherein the magnetic resonance imaging system comprises a magnet for generating a magnetic field within the imaging zone,
wherein the radiotherapy apparatus is adapted for rotating the radiotherapy source at least partially around the subject support,
wherein execution of the instructions causes the processor to repeatedly:
acquire the magnetic resonance data using the magnetic resonance imaging system;
reconstruct a magnetic resonance image from the magnetic resonance data;
register a location of the target zone in the magnetic resonance image;
generate radiotherapy control signals in accordance with the location of the registered target zone,
wherein the radiotherapy control signals cause the radiotherapy source to irradiate the target zone,
wherein the radiotherapy control signals cause an angular rotation of the rotatable collimator member and the angular rotation at least partially controls the location of a beam path of the radiotherapy source in the target zone;

generate mechanical positioning control signals in accordance with the registered target zone and the radiotherapy control signals, wherein the mechanical positioning control signals cause the mechanical positioning system to position the subject; and
send the radiotherapy control signals to the radiotherapy system and send the mechanical positioning control signals to the mechanical positioning system.

13. A method of controlling a therapeutic apparatus,
wherein the therapeutic apparatus comprises a radiotherapy apparatus for treating a target zone of a subject,
wherein the radioth

Assignees

• Uhlemann Falk
• Koninl Philips Electronics Nv

Inventors

• Uhlemann Falk

Classifications

• A61N5/1077

  Beam delivery systems · CPC title

• A61N2005/1055

  using magnetic resonance imaging [MRI] · CPC title

• A61N5/1067

  in real time, i.e. during treatment · CPC title

• A61N2005/1095

  Elements inserted into the radiation path within the system, e.g. filters or wedges · CPC title

• A61B2090/374

  NMR or MRI · CPC title