Systems and methods for calibrating gain in an electron multiplier

US9508534B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9508534-B2
Application numberUS-201414535937-A
CountryUS
Kind codeB2
Filing dateNov 7, 2014
Priority dateNov 7, 2014
Publication dateNov 29, 2016
Grant dateNov 29, 2016

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Abstract

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Method for operating a mass spectrometer includes supplying a quantity of ions to an ion detector. The ion detector can include a conversion dynode operating in a first polarity and an electron multiplier. The method further includes adjusting the gain of the electron multiplier to determine a first set of calibration parameters, and calculating a second set of calibration parameters for the electron multiplier from the first set of calibration parameters. The second set of calibration parameters are for a second polarity of the conversion dynode. The method can further include configuring the ion detector to operate at the second polarity based on the second set of calibration parameters, and supplying ions of the second polarity to the mass spectrometer, and detecting an ion at a particular mass to charge ratio using the ion detector.

First claim

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What is claimed is: 1. A method of operating a mass spectrometer, comprising: supplying a quantity of ions to an ion detector, the ion detector including a conversion dynode operating in a first polarity and an electron multiplier; calibrating the gain of the electron multiplier to determine a first set of calibration parameters; calculating a second set of calibration parameters for the electron multiplier from the first set of calibration parameters, the second set of calibr…

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What does patent US9508534B2 cover?
Method for operating a mass spectrometer includes supplying a quantity of ions to an ion detector. The ion detector can include a conversion dynode operating in a first polarity and an electron multiplier. The method further includes adjusting the gain of the electron multiplier to determine a first set of calibration parameters, and calculating a second set of calibration parameters for the el…
Who is the assignee on this patent?
Thermo Finnigan Llc
What technology area does this patent fall under?
Primary CPC classification H01J49/0009. Mapped technology areas include Electricity.
When was this patent published?
Publication date Tue Nov 29 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).