Aliquotter system and workflow

Patent metadata

Field	Value
Publication number	US-9506943-B2
Application number	US-201213671405-A
Country	US
Kind code	B2
Filing date	Nov 7, 2012
Priority date	Nov 7, 2011
Publication date	Nov 29, 2016
Grant date	Nov 29, 2016

Abstract

A system is disclosed. The system includes an aliquotter module. The aliquotter module includes a track including: a travel lane; a first loop; and a second loop configured to transport sample carriers with primary sample containers. The aliquotter module can further include a pipettor that can aspirate a first aliquot volume of a sample in a primary sample container located in an aspiration position and dispense the first aliquot volume of the sample in a secondary sample container located in a dispensing position. The aliquotter module can cause the secondary sample container to leave the aliquotter module before the primary sample container.

First claim

What is claimed is:

1. A system comprising:
an aliquotter module comprising
a track comprising
a travel lane configured to transport sample carriers with primary sample containers and sample carriers with secondary sample containers,
a first loop configured to transport empty sample carriers, sample carriers with empty secondary sample containers and sample carriers with secondary sample containers comprising sample aliquots, wherein the first loop is connected to the travel lane such that the sample carriers can enter the first loop from the travel lane and leave the first loop onto the travel lane, and
a second loop configured to transport sample carriers with primary sample containers, wherein the second loop is connected to the travel lane such that sample carriers can enter the second loop from the travel lane and leave the second loop onto the travel lane, and

a pipettor,
a processor configured to control the pipettor to aspirate a first aliquot volume of a sample in a primary sample container located in an aspiration position and dispense the first aliquot volume of the sample in a secondary sample container located in a dispensing position, wherein the first loop does not include the aspiration position, and wherein the first loop includes the dispensing position, and
the processor further configured to control the aliquotter module to cause the secondary sample container to return to the travel lane before the primary sample container returns to the travel lane.

2. The system of claim 1 , wherein the track comprises a common track portion connecting to the first loop and the second loop.

3. The system of claim 1 , further comprising:
a first rotatable gateway device proximate the travel lane and the first loop; and
a second rotatable gateway device proximate the travel lane and the second loop,
wherein the first rotatable gateway device is operable to transfer a sample carrier from the travel lane to the first loop and from the first loop to the travel lane, and
wherein the second rotatable gateway device is operable to transfer a sample carrier from the travel lane to the second loop and from the second loop to the travel lane.

4. The system of claim 3 , wherein each of the first and second rotatable gateway devices comprise a disk-like object having a crescent shape with a concave surface for receiving a circular edge of a sample carrier.

5. The system of claim 1 , wherein the first loop and the second loop are circular endless loops, having no common track portion connecting to the travel lane.

6. The system of claim 1 , further comprising sample carriers, wherein the sample carriers are independently movable carriers.

Assignees

• Beckman Coulter Inc

Inventors

• Müller Martin
• Johns Charles W
• Eberhardt Michael

Classifications

• B65G2201/0261

  Puck as article support · CPC title

• G01N2035/0489

  Self-propelled units · CPC title

• G01N2035/1032

  Dilution or aliquotting · CPC title

• G01N2035/1025

  Fluid level sensing · CPC title

• G01N2035/0491

  Position sensing, encoding; closed-loop control · CPC title