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High-throughput platform for in-vivo sub-cellular screens on vertebrate larvae
US9506912B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9506912-B2 |
| Application number | US-201414518070-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 20, 2014 |
| Priority date | Feb 26, 2010 |
| Publication date | Nov 29, 2016 |
| Grant date | Nov 29, 2016 |
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Abstract
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High throughput system for in vivo screens on vertebrate larvae. The system includes a source of vertebrate larvae in a liquid medium and loading tube means for aspirating a larva. A detector assembly is provided to differentiate passage of a larva from bubbles and/or debris. An imaging means is provided for both confocal imaging and wide-field fluorescence imaging of the larva. A laser is provided for optical manipulation of the larva.
First claim
Opening claim text (preview).
What is claimed is: 1. A high-throughput system for in vivo screens comprising: a source of a specimen organism in a liquid medium; a pump configured to load the specimen organism in the liquid medium into a transparent tube; an automatic optical means to position the specimen organism in the transparent tube within a field-of-view of an imaging apparatus for microscopy through the transparent tube; and a motor and capillary assembly operable to rotate the transparent tube,…
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Chemistry & Metallurgy · mapped topic
Physics · mapped topic
- G01N33/5088Primary
Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
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- What does patent US9506912B2 cover?
- High throughput system for in vivo screens on vertebrate larvae. The system includes a source of vertebrate larvae in a liquid medium and loading tube means for aspirating a larva. A detector assembly is provided to differentiate passage of a larva from bubbles and/or debris. An imaging means is provided for both confocal imaging and wide-field fluorescence imaging of the larva. A laser is prov…
- Who is the assignee on this patent?
- Massachusetts Inst Technology
- What technology area does this patent fall under?
- Primary CPC classification G01N33/5088. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Nov 29 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).