Prolylhydroxylase inhibitors and methods of use

US9505741B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9505741-B2
Application numberUS-201113579646-A
CountryUS
Kind codeB2
Filing dateFeb 17, 2011
Priority dateFeb 17, 2010
Publication dateNov 29, 2016
Grant dateNov 29, 2016

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  5. First independent claim

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Abstract

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Compounds for inhibiting hypoxia inducible factor (HIF) prolyl-4-hydroxylases (PHDs) having the general formula (1). Methods of using these and related compounds for treating a patient having a condition that would benefit from inhibiting HIF PHD are also described herein.

First claim

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What is claimed is: 1. A method for treating a patient having brain ischemia, the method comprising administering to said patient in need thereof an effective amount of a HIF prolyl-4-hydroxylase inhibiting compound within the following general formula: wherein: R 1 is a monocyclic group, wherein said monocyclic group is optionally substituted with one or more groups…

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What does patent US9505741B2 cover?
Compounds for inhibiting hypoxia inducible factor (HIF) prolyl-4-hydroxylases (PHDs) having the general formula (1). Methods of using these and related compounds for treating a patient having a condition that would benefit from inhibiting HIF PHD are also described herein.
Who is the assignee on this patent?
Ratan Rajiv R, Gazaryan Irina, Smirnova Natalya, and 1 more
What technology area does this patent fall under?
Primary CPC classification C07D401/12. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Nov 29 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).