Medicated module for a drug delivery device

Patent metadata

Field	Value
Publication number	US-9504627-B2
Application number	US-201214112447-A
Country	US
Kind code	B2
Filing date	Apr 19, 2012
Priority date	Apr 21, 2011
Publication date	Nov 29, 2016
Grant date	Nov 29, 2016

Abstract

A medicated module includes (i) a rotatable reservoir body comprising (a) a flow path and (b) a medicament-reservoir profile and (ii) a pin feature disposed in the rotatable reservoir body, the pin feature comprising a medicament-cavity profile. The medicated module also includes a second medicament, wherein the second medicament is held in a reservoir formed at least in part by the medicament-reservoir profile and the medicament-cavity profile, and wherein, prior to dispense, the second medicament is filled to at least the proximal end of the medicament-cavity profile.

First claim

The invention claimed is:

1. A medicated module attachable to a drug delivery device, the drug delivery device having a drug reservoir holding a first medicament, the medicated module comprising:
an outer body that houses a rotatable reservoir body that is rotatable with respect to the outer body;
a second medicament;
a proximal needle at the outer body, wherein the proximal needle is configured to establish fluid communication with the drug reservoir of the drug delivery device when the medicated module is attached to the drug delivery device;
a distal needle attached to the rotatable reservoir body, wherein the distal needle is configured to act as an output needle, through which a dose of the first medicament and the second medicament can be injected; and
a pin feature disposed in the rotatable reservoir body, the pin feature comprising a medicament-cavity profile and a bypass flow path, wherein the pin feature is rotationally fixed to the outer body;
wherein the rotatable reservoir body comprises (i) a flow path traveling from a proximal end to a distal end of the rotatable reservoir body, and (ii) a medicament-reservoir profile, wherein the rotatable reservoir body is axially fixed to the outer body;
wherein the second medicament is held in a reservoir region formed at least in part by the medicament-reservoir profile and the medicament-cavity profile, and wherein, prior to dispense, the second medicament is filled to at least a proximal end of the medicament-cavity profile; and
wherein the rotatable reservoir body is configured to rotate with respect to the pin feature from a priming mode to an injection mode such that (i) prior to dispense, (a) the bypass flow path is initially in communication with the flow path such that the drug delivery device may be primed with the first medicament by forcing a priming dose of the first medicament through the bypass flow path, and (b) the medicament-cavity profile is in communication with the reservoir profile, and such that and (ii) during dispense, the medicament-cavity profile is in communication with the flow path such that the first and the second medicament may be delivered through the distal needle.

2. The medicated module of claim 1 , wherein the outer body comprises a keyed spigot, and wherein the pin feature comprises a corresponding keyed recess configured to engage with the keyed spigot.

3. The medicated module of claim 1 , further comprising a proximal plate feature, wherein the proximal plate feature is rotationally fixed to the rotatable reservoir body, wherein the proximal plate feature is configured to seal the second medicament.

4. The medicated module of claim 3 , wherein the proximal plate feature comprises at least one hole to permit flow into the rotatable reservoir body.

5. The medicated module of claim 4 , wherein the proximal plate feature comprises a groove configured allow for the first medicament to flow from a proximal needle to the hole.

6. The medicated module of claim 2 , wherein the proximal plate feature comprises a hole configured to permit the proximal plate feature to rotate relative to the keyed spigot of the outer body.

7. The medicated module of claim 6 , wherein the proximal plate feature is keyed to the rotatable reservoir body such that the proximal plate feature is rotationally fixed.

8. The medicated module of claim 1 , further comprising a needle guard, wherein the needle guard is configured to rotate the rotatable reservoir body as the needle guard is moved in a proximal direction.

9. The medicated module of claim 8 , wherein the needle guard comprises a tooth feature, wherein the rotatable reservoir body comprises helical cam surface configured to interact with the tooth feature as the needle guard rotates the rotatable reservoir body.

10. The medicated module of claim 1 , wherein the second medicament dispensed from the medicated module is medicament stored in the medicament cavity profile.

11. The medicated module of claim 1 , wherein rotation of the rotatable body causes the second medicament stored in the medicament cavity profile to be isolated from the rest of the second medicament, wherein the volume of the second medicament that is isolated is less than the total volume of the medicament filled into the medicated module.

12. The medicated module of claim 1 , wherein the medicament-reservoir profile and the flow path are cut-outs from the generally cylindrical interior of the reservoir body and
wherein the medicament-cavity profile and the bypass flow path are formed by cut-outs from the generally cylindrical outer surface of the pin feature;
wherein
(i) prior to dispense, (a) the bypass flow path is initially rotationally aligned with the flow path such that the drug delivery device may be primed with the first medicament by forcing a priming dose of the first medicament through the bypass flow path and (b) the medicament-cavity profile is rotationally aligned with the reservoir profile,
wherein
(ii) during dispense, the medicament-cavity is rotationally alighted with the flow path.

Assignees

• Young Alasdair George
• De Sausmarez Lintell Daniel Thomas
• Mercer David Richard
• Sanofi Aventis Deutschland

Inventors

• Young Alasdair George
• De Sausmarez Lintell Daniel Thomas
• Mercer David Richard

Classifications

• A61M5/504

  for blocking the fluid passageway · CPC title

• A61M2005/1787

  Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid · CPC title

• A61M2205/583

  by visual feedback · CPC title

• A61M5/326

  Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user · CPC title

• A61M5/3294

  comprising means for injection of two or more media, e.g. by mixing · CPC title