Piperidinone carboxamide indane CGRP receptor antagonists

US9499541B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9499541-B2
Application numberUS-201414505255-A
CountryUS
Kind codeB2
Filing dateOct 2, 2014
Priority dateNov 12, 2010
Publication dateNov 22, 2016
Grant dateNov 22, 2016

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

First claim

Opening claim text (preview).

What is claimed is: 1. A compound which is: or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition which comprises an inert carrier and a compound of claim 1 , or a pharmaceutically acceptable salt thereof. 3. A method of treating headache in a mammalian patient in need of such treatment, which comprises administering to the patient a therapeutically effective amount of a compound of claim 1 or a pharmaceutically acceptable salt thereof.

Assignees

Inventors

Classifications

  • Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

  • Ortho-condensed systems · CPC title

  • C07D471/04Primary

    Ortho-condensed systems · CPC title

  • not condensed and containing further heterocyclic rings · CPC title

  • Centrally acting analgesics, e.g. opioids · CPC title

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Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US9499541B2 cover?
The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of su…
Who is the assignee on this patent?
Merck Sharp & Dohme
What technology area does this patent fall under?
Primary CPC classification C07D471/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Nov 22 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).