Heterocyclic modulators of lipid synthesis
US-2024400552-A1 · Dec 5, 2024 · US
US9499541B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9499541-B2 |
| Application number | US-201414505255-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 2, 2014 |
| Priority date | Nov 12, 2010 |
| Publication date | Nov 22, 2016 |
| Grant date | Nov 22, 2016 |
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The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
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What is claimed is: 1. A compound which is: or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition which comprises an inert carrier and a compound of claim 1 , or a pharmaceutically acceptable salt thereof. 3. A method of treating headache in a mammalian patient in need of such treatment, which comprises administering to the patient a therapeutically effective amount of a compound of claim 1 or a pharmaceutically acceptable salt thereof.
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
Ortho-condensed systems · CPC title
Ortho-condensed systems · CPC title
not condensed and containing further heterocyclic rings · CPC title
Centrally acting analgesics, e.g. opioids · CPC title
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