Processes for preparing tetrahydroisoquinolines
US-2016022675-A1 · Jan 28, 2016 · US
US9498476B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9498476-B2 |
| Application number | US-201514841024-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 31, 2015 |
| Priority date | Jun 4, 2008 |
| Publication date | Nov 22, 2016 |
| Grant date | Nov 22, 2016 |
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The present disclosure generally relates to a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. The present disclosure also generally relates to pharmaceutical compositions comprising the crystalline form, as well of methods of using a crystalline form in the treatment of depression and other conditions and methods for obtaining such crystalline form.
Opening claim text (preview).
What is claimed is: 1. A method of treating depression in a mammal in need thereof comprising administering to the mammal a therapeutically-effective amount of Form N-1 of 2. The method of claim 1 wherein the mammal is a human.
directly linked by a ring-member-to-ring-member bond · CPC title
not condensed and containing further heterocyclic rings · CPC title
having six-membered rings with two {or more} nitrogen atoms as the only ring heteroatoms, e.g. piperazine {or tetrazines}(A61K31/48 takes precedence {; with three nitrogen atoms A61K31/53}) · CPC title
having six-membered rings with one nitrogen as the only ring hetero atom · CPC title
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