Methods using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias

US9498472B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9498472-B2
Application numberUS-201514729934-A
CountryUS
Kind codeB2
Filing dateJun 3, 2015
Priority dateMay 17, 2002
Publication dateNov 22, 2016
Grant dateNov 22, 2016

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Abstract

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Methods of treating, preventing or managing leukemias are disclosed. The methods encompass the administration of an immunomodulatory compound of the invention known as Revlimid® or lenalidomide. The invention further relates to methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods of the invention are also disclosed.

First claim

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What is claimed is: 1. A method of treating acute myelogenous leukemia in a human, which comprises cyclically administering for 21 days followed by seven days rest in a 28 day cycle to a human having acute myelogenous leukemia a therapeutically effective amount of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione, or a pharmaceutically acceptable salt or solvate thereof at an amount of about 1 mg/day to about 50 mg/day. 2. The method of claim 1 ,…

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What does patent US9498472B2 cover?
Methods of treating, preventing or managing leukemias are disclosed. The methods encompass the administration of an immunomodulatory compound of the invention known as Revlimid® or lenalidomide. The invention further relates to methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. Pharmaceutical compositions and sin…
Who is the assignee on this patent?
Celgene Corp
What technology area does this patent fall under?
Primary CPC classification A61K31/454. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Nov 22 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).