Methods using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias
US-9056103-B2 · Jun 16, 2015 · US
US9498472B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9498472-B2 |
| Application number | US-201514729934-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 3, 2015 |
| Priority date | May 17, 2002 |
| Publication date | Nov 22, 2016 |
| Grant date | Nov 22, 2016 |
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Methods of treating, preventing or managing leukemias are disclosed. The methods encompass the administration of an immunomodulatory compound of the invention known as Revlimid® or lenalidomide. The invention further relates to methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods of the invention are also disclosed.
Opening claim text (preview).
What is claimed is: 1. A method of treating acute myelogenous leukemia in a human, which comprises cyclically administering for 21 days followed by seven days rest in a 28 day cycle to a human having acute myelogenous leukemia a therapeutically effective amount of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione, or a pharmaceutically acceptable salt or solvate thereof at an amount of about 1 mg/day to about 50 mg/day. 2. The method of claim 1 ,…
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