Romidepsin solid forms and uses thereof
US-9518094-B2 · Dec 13, 2016 · US
Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates
US9493512B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9493512-B2 |
| Application number | US-201514686899-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 15, 2015 |
| Priority date | Oct 9, 2012 |
| Publication date | Nov 15, 2016 |
| Grant date | Nov 15, 2016 |
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- Title
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- Abstract
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Abstract
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The invention relates to a method or process for solution phase chemical manufacture of depsipeptides of the formula I, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound selected from the group consisting of compounds with the following formulae, or a salt thereof: 2. The compound of claim 1 , or a salt thereof, which is: 3. The compound of claim 1 , or a salt thereof, which is: 4. The compound of claim 1 , or a salt thereof, which is: 5. The compound of claim 1 , or a salt thereof, which is: 6. The compound of claim 1 , or a salt thereof, which is: 7. The compound of claim 1 , or a salt thereof, which is: 8. The compound of claim 1 , or a salt thereof, which is: 9. The compound of claim 1 , or a salt thereof, which is:
Assignees
Inventors
Classifications
with the first amino acid being acidic · CPC title
of a saturated carbon skeleton · CPC title
Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00) · CPC title
having 5 to 11 amino acids · CPC title
- C07K11/02Primary
cyclic, e.g. valinomycins {; Derivatives thereof} · CPC title
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Frequently asked questions
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- What does patent US9493512B2 cover?
- The invention relates to a method or process for solution phase chemical manufacture of depsipeptides of the formula I, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
- Who is the assignee on this patent?
- Acemoglu Murat, Hellstern Heribert, Kollmer Felix, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification C07K11/02. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Nov 15 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).