Medicament delivery device with dispense interface sensor and method controlling the device

Patent metadata

Field	Value
Publication number	US-9492616-B2
Application number	US-201214119211-A
Country	US
Kind code	B2
Filing date	May 24, 2012
Priority date	May 25, 2011
Publication date	Nov 15, 2016
Grant date	Nov 15, 2016

Abstract

A medicament delivery device is shown for the administration of one or more drug agents. The device comprises a medicament cartridge retainer for holding a medicament cartridge. A dispense interface can be attached to an attachment of the device for facilitating fluidic communication from the device. Further, an interface sensor is configured to provide an output indicative of whether the dispense interface is attached to the attachment. The device also comprises a piston rod for driving a bung of the medicament cartridge, and a drive train for advancing the piston rod to the bung. A controller is configured to control the drive train to advance the piston rod towards the bung when the output of the interface sensor indicates that the dispense interface is not on the attachment. The controller is further configured to disable advancement of the piston rod when the output of the interface sensor indicates that the dispense interface is at least partially on the attachment.

First claim

The invention claimed is:

1. A medicament delivery device for the administration of one or more drug agents, the device comprising
a medicament cartridge retainer for holding a medicament cartridge,
an attachment for attachment thereto of a dispense interface, the dispense interface for providing an exit pathway for the medicament contained in the cartridge,
an interface sensor configured to provide an output indicative of whether the dispense interface is attached to the attachment,
a piston rod for driving a bung of the medicament cartridge,
a drive train for advancing the piston rod to the bung,
a controller configured to control the drive train to advance the piston rod towards the bung when the output of the interface sensor indicates that the dispense interface is not on the attachment and to disable advancement of the piston rod when the output of the interface sensor indicates that the dispense interface is at least partially on the attachment,
wherein the controller is operative to sense stalling of the drive train,
wherein the stalling of the drive train occurs upon contact between the piston rod and the bung, following the piston rod not being in contact with the bung, and
wherein the controller is further configured to stop the drive train when stalling of the drive train is sensed.

2. A medicament delivery device according to claim 1 , wherein the controller is operative to monitor the output signal of the interface sensor during advancement of the piston rod and disable advancement of the piston rod if, during advancement thereof, the interface sensor indicates at least partial attachment of the dispense interface.

3. A medicament delivery device according to claim 1 comprising first and second medicament cartridge retainers each for holding a medicament cartridge.

4. A medicament delivery device according to claim 3 , wherein the dispense interface provides fluidic communication from the first and second medicament cartridge retainers to an outlet of the device.

5. A medicament delivery device according to claim 1 , wherein the controller is operative to advance the piston rod following a cartridge change.

6. A medicament delivery device according to claim 1 , wherein the device is hand-held.

7. A medicament delivery device according to claim 6 , wherein the device is a pen-type injection device.

8. A medicament delivery device according to claim 1 , wherein the interface sensor comprises first and second detectors for detecting partial or complete removal of the dispense interface, or partial or complete attachment of the dispense interface.

9. A medicament delivery device according to claim 8 , wherein the first detector is activated when the dispense interface is partially attached to the attachment and the second detector is activated when the dispense interface is completely attached to the attachment.

10. A medicament delivery device according to claim 9 , wherein the second detector is deactivated when the dispense interface is partially removed, and the first detector is deactivated when the dispense interface is completely removed from the attachment.

11. A method for controlling a medicament delivery device comprising a medicament cartridge retainer for holding a medicament cartridge, an attachment for attachment thereto of a dispense interface, the dispense interface for providing an exit pathway for the medicament contained in the cartridge, an interface sensor configured to provide an output indicative of whether the dispense interface is attached to the attachment, a piston rod for driving a bung of the medicament cartridge, a drive train for advancing the piston rod to the bung, and a controller configured to control operation of the device, wherein the controller is operative to sense stalling of the drive train, the method comprising: sensing the output of the interface sensor; determining whether the sensed output indicates whether the dispense interface is or is not at least partially attached to the attachment; advancing the piston rod when the sensed output indicates that the dispense interface is not attached; stopping or disabling advancement of the piston rod when the output of the interface sensor indicates that the dispense interface is at least partially attached; and stopping the drive train when stalling of the drive train is sensed, wherein the stalling of the drive train occurs upon contact between the piston rod and the bung, following the piston rod not being in contact with the bung.

Assignees

• Eggert Ilona
• Langley Christopher Nigel
• Day Shane Alistair
• Sanofi Aventis Deutschland

Inventors

• Eggert Ilona
• Langley Christopher Nigel
• Day Shane Alistair

Classifications

• A61M5/16831 Primary

  Monitoring, detecting, signalling or eliminating infusion flow anomalies (low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066) · CPC title

• A61M2005/14268

  with a reusable and a disposable component · CPC title

• A61M5/2066

  comprising means for injection of two or more media, e.g. by mixing · CPC title

• A61M2205/50

  with microprocessors or computers · CPC title

• A61M2205/14

  Detection of the presence or absence of a tube, a connector or a container in an apparatus · CPC title